Toby Prevost

Professor

    • 9167
      Citations

    Personal profile

    Biographical details

    Toby Prevost was appointed in May 2020 to the newly created "Nightingale-Saunders Chair of Complex Clinical Trials and Statistics", and Director of the Nightingale-Saunders Clinical Trials and Epidemiology Unit, at King's College London.

     

    He was previously (2016-2020) a Chair in Clinical Trials and Medical Statistics at Imperial College London, leading Statistics in the Imperial Clinical Trials Unit; and Reader (2009-2012) then Professor (2012-2015) of Medical Statistics at King's College London. Inaugural lecture: https://www.youtube.com/watch?v=3K8U0Vbr2zs

     

    Toby joined King's in an academic post from 2009 from the University of Cambridge, where he worked in the nationwide Health and Lifestyle Survey multidiciplinary team (1991-3, Research Assistant), underook statistical consulting in the "CAMS" Centre for Applied Medical Statistics (1996-2002, Research Associate).

     

    Funding from the MRC (through a Complex Interventions group co-operative grant led by Prof Ann-Louise Kinmonth) enabled secondment to work in statistical research (clustering in trials, and meta-analysis for complex intervention development) in the Cambridge MRC Biostatistics Unit (2002-6, Senior Research Scientist), with Prof Simon Thompson and Prof David Spiegelhalter.

     

    Toby contributed to complex intervention trials in the University of Cambridge's General Practice and Primary Care Research Unit (2000-9, Senior Research Associate from 2002) and was a Senior Medical Statistician within the CAMS consulting unit (2006-2009).

     

    Toby's degrees were at the University of Southampton: BSc in Mathematics with Statistics (1990), MSc in Statistics with Applications in Medicine (1991), and PhD in Social Statistics (1996) - multilevel modelling of child mortality (Developing Bayesian approaches to estimating the predictors, and comparing these to classical methods).

     

    Toby has contributed in an advisory capacity as a member on NICE committees examining and interpeting published research evidence for national guidance: NICE Public Health Interventions Advisory Committee (2008-2013); NICE Public Health Advisory Committee (2013-2020); Expert Panel Member of the SACN (Scientific Advisory Committee on Nutrition) with NICE Rapid Guideline for Vitamin D and Covid-19 (2020).

     

    He has contributed also at the early stages of research, as a member of Funding Committees for health research: NIHR Public Health Research Funding Committee (2014-2020); NIHR Covid-19 Recovery and Learning Funding Committee (2020); Cancer Research UK Prevention & Population Expert Review Panel (2021); European Funding Board for sub-macular haemorrhage for EURETINA/Fight for Sight.

     

    Toby has received support from the NIHR in granted studies and has contributed to NIHR: NIHR Public Health Research Applications and Design Advisor (2020-2023), London NIHR Research Design Service advisor (2011-2015 and 2022-2023); Independent Advisory Board member for the NIHR Central-region PHIRST CONNECT (Public Health Interventions Responsive Studies Team, 2021 to date); and has volunteered as an independent member of 25 oversight committees for NIHR-funded clinical trials committees around the country since 2009.

     

    Published research listed in Scopus: https://www.scopus.com/authid/detail.uri?authorId=7004917424

    Scopus H-Index: 57

     

    A selection of research by area (with statisticial co-workers shown in bold):

     

    Palliative and End of Life Care and Nurse-led interventions

     

    PrimaryBreathe: programme to develop and test a brief remote primary care intervention for chronic breathlessness. Principal Investigator (PI): Anna Spathis (Cambridge). NIHR Programme Grants for Applied Research £2.4M (1/9/22; 60m).

     

    PAM: Randomised controlled trial of a very brief nurse-led intervention followed by a text message or a smartphone app to support medication adherence in people prescribed treatment for hypertension in primary care. PI: Stephen Sutton (Cambridge) NIHR Programme Grants for Applied Research £2M (1/6/2017; 87 months)

     

    INSPIRE: INtegrated Short-term PallIative REhabilitation to improve quality of life and equitable care access in incurable cancer. PI: Matt Maddocks (KCL). EU Horizon and UKRI £3.8M (1/9/22; 48m)

     

    NIHR Global Health Research Group On Global Health And Palliative Care (GHAP): Expanding Access. PI: Richard Harding (KCL), £2.7m (1/2/22; 48m).

     

    NIHR Research for Patient Benefit funded, £250k. PI: Morag Farquhar. Two trials with authors: Farquhar M, Prevost AT, McCrone P, Brafman-Price B, Bentley A, Higginson IJ, Todd C, Booth S.

    (1) The clinical and cost-effectiveness of a Breathlessness Intervention Service for patients with advanced non-malignant disease and their informal carers - mixed findings of a mixed method randomised controlled trial. Trials 2016 Apr;17:185.

    (2) Is a specialist breathlessness service more effective and cost-effective for patients with advanced cancer and their carers than standard care? Findings of a mixed-method randomised controlled trial.  BMC Medicine. 2014;12:194.

     

    Farmer A, Hardeman W, Hughes D, Prevost AT, Kim Y, Craven A, Oke J, Boase S, Selwood M, Kellar I, Graffy J, Griffin S, Sutton S, Kinmonth AL. An explanatory randomised controlled trial of a nurse-led, consultation-based intervention to support patients with adherence to taking glucose lowering medication for type 2 diabetes. BMC Family Practice 2012;13:30. MRC funded. Co-PIs: Ann-Louise Kinmonth and Andrew Farmer

     

    Gelling L, Prevost AT. The needs of relatives of critically ill patients admitted to a neurosciences critical care unit: A comparison of the perceptions of relatives, nurses and doctors. Care of the Critically Ill 1999;15:53-58

     

    Robinson SM, Mackenzie-Ross S, Campbell-Hewson GL, Egleston CV, Prevost AT. Psychological effect of witnessed resuscitation on bereaved relatives. The Lancet 1998;352:614-7

     

    India and UK Diabetic Retinopathy Collaboration. PI: Sobha Sivaprasad. RCUK(MRC) funded

     

    Gurudas S, Vasconcelos JC, Prevost AT, Raman R, Rajalakshmi R, Ramasamy K, Mohan V, Rani PK, Das T, Conroy D, Tapp RJ, Sivaprasad S, on behalf of SMART-India Study Collaborators. National prevalence of vision impairment and blindness and associated risk factors in adults aged 40 years and older with known or undiagnosed diabetes: results from the SMART-India cross-sectional study. Lancet Global Health 2024 Feb 28:S2214-109X(24)00035-4

     

    Raman R, Vasconcelos JC, Rajalakshmi R, Prevost AT, Ramasamy,  Mohan KV, Mohan D, Rani PK, Conroy D, Das T, Sivaprasad S. Prevalence of diabetes retinopathy in India stratified by known and undiagnosed diabetes, unban and rural locations, and socio-economic indices: results from the SMART India population-based cross-sectional screening study. Lancet Global Health 2022 Dec;10(12):e1764-e1773 doi: 10.1016/S2214-109X(22)00411-9.

     

    Rajalakshmi R, Vasconcelos JC, Prevost AT, Sivaprasad S, Deepa M, Raman R,  Ramasamy K, Anjana RM, Conroy D, Das T, Hanif W, Mohan KV, Mohan V.  Burden of undiagnosed and sub-optimally controlled diabetes in selected regions of India: Results from the SMART India population-level diabetes screening study. Diabetic Medicine 2023 Jun 12:e15165

     

    Nugawela MD, Gurudas S, Prevost AT, Mathur R, Robson J, Sathish T, Rafferty JM, Rajalakshmi R, Anjana RM, Jebarani S, Mohan V, Owens DR, Sivaprasad S. Development and validation of predictive risk models for sight threatening diabetic retinopathy in patients with type 2 diabetes to be applied as triage tools in resource limited settings. EClinicalMedicine 2022;51:101578.

     

    Gurudas S, Maheshwari JJ, Revathy YR, Frudd K, Sivaprasad S, Ramanathan SM, Pooleeswaran V, Prevost AT, Karatsai E, Halim S, Chandra S, Nderitu P, Conroy D, Krishnakumar S, Parameswaran S, Dharmalingam K, Ramasamy K, Raman R, Jones C, Eleftheriadis H, Greenwood J, Turowski P. Multicentre Evaluation of diagnostic circulating biomarkers to detect sight-threatening diabetic retinopathy. JAMA Ophthalmology 2022; May 5:e221175.

     

    Gurudas S, Nugawela M, Prevost AT, Sathish T, Mathur R, Rafferty JM, Blighe K, Rajalakshmi R, Mohan AR, Saravanan J, Majeed A, Mohan V, Owens DR, Robson J, Sivaprasad S. Development and validation of resource-driven risk prediction models for incident chronic kidney disease in type 2 diabetes. Scientific Reports 2021;11:13654

     

    Other Ophthalmology Research

     

    PINNACLE: Deciphering AMD by deep phenotyping and machine learning. PI: Andrew Lotery (Southampton) Wellcome Trust Collaborative Award in Science. Involvement in the prospective cohort study with statistical prediction modelling element.

     

    Hykin P, Prevost AT, Vasconcelos JC, Murphy C, Kelly J, Ramu J, Hounsome B, Yang Y, Harding SP, Lotery A, Chakravarthy U, Sivaprasad S; LEAVO Study Group. Clinical Effectiveness of Intravitreal Therapy With Ranibizumab vs Aflibercept vs Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion: A Randomized Clinical Trial. JAMA Ophthalmology 2019 Aug 29. NIHR HTA funded. PI: Phil Hykin. King's CTU

     

    Sivaprasad S, Vasconcelos JC, Prevost AT, Holmes H, Hykin P, George S, Murphy C, Kelly J, Arden GB. Clinical efficacy and safety of a light mask for prevention of dark adaption in treating and preventing progression of early diabetic macular oedema at 24 months (CLEOPATRA): a multicentre, phase 3, randomised controlled trial. Lancet Diabetes & Endocrinology 2018;6:382-391. NIHR/MRC EME funded. PI: Sobha Sivaprasad. King's CTU

     

    Sivaprasad S, Prevost AT, Vasconcelos JC, Riddell A, Murphy C, Kelly J, Bainbridge J, Tudor-Edwards R, Hopkins D, Hykin P. Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial. The Lancet 2017;389:2193-2203. NIHR/MRC EME funded. PI: Sobha Sivaprasad. King's CTU

    This research paper was selected as a finalist for the 2018 BMJ Awards Research Paper of the Year (final 6).

     

    Rheumatology Trials and Methods Research

     

    ALTO: Arthritis prevention in the pre-clinical phase of RA with Abatacept – Long Term Outcome Study. PI: Andrew Cope (KCL) Bristol-Myers Squibb

     

    Cope AP, Jasenecova M, Vasconcelos JC, Filer A, Raza K, Qureshi S, D’Agostino MA, McInnes IB, Isaacs JD, Pratt AG, Fisher BA, Buckley CD, Emery P, Ho P, Buch MH, Ciurtin C, van Schaardenburg D, Huizinga T, Toes R, Georgiou E, Kelly J, Murphy C, Prevost AT, on behalf of the APIPPRA Study Investigators, Abatacept in individuals at high risk of rheumatoid arthritis: a randomised, multi-centre, placebo-controlled phase 2B interception trial. The Lancet 2024; Feb 13: S0140-6736(23)02649-1. King's CTU.

     

    Ibrahim F, Tom BDM, Scott DL, Prevost AT. Characterization of missing data patterns and mechanisms in longitudinal composite outcome trial in Rheumatoid Arthritis. Ther Adv Musculoskelet Dis. 2022;14:1759720X221114103

     

    Ibrahim F, Tom BDM, Scott DL, Prevost AT. A systematic review of randomised controlled trials in rheumatoid arthritis: the reporting and handling of missing data in composite outcomes. Trials 2016 Jun;17(1):272. PhD Studentship.

     

    Kirkham B, Chaabo K, Hall C, Garrood T, Mant T, Allen E, Vincent A, Vasconcelos JC, Prevost AT, Panayi GS, Corrigall VM. Safety and patient response as indicated by biomarker changes to BiP in the Phase I/IIa RAGULA clinical trial in rheumatoid arthritis. Rheumatology 2016 Nov;55(11):1993-2000.

     

    Richards CA, Prevost AT, Speed CA, Hazleman BL, Östör AJK. Diagnosis and relation to general health of shoulder disorders presenting to primary care. Rheumatology, 2005, 44, 800–5.

     

    Methods research for clustered data and Cluster Randomised Trials in various research areas

     

    Turner RM, Prevost AT, Thompson SG. Allowing for imprecision of the intracluster correlation coefficient in the design of cluster randomised trials. Statistics in Medicine 2004;23:1195-1214

     

    Prevost AT. PhD in Social Statistics: Multilevel Modelling of child mortality (1996) comparing Bayesian and Classical methods for analysing clustered binary outcome data. University of Southampton PhD thesis abstract: https://eprints.soton.ac.uk/460252/

     

    Jawad S, Modi N, Prevost AT, Gale C. A systematic review identifying common data items in neonatal trials and assessing their completeness in routinely recorded United Kingdom national neonatal data. Trials 2019;20:731

     

    Simmons RK, Echouffo-Tcheugui JB, Sharp SJ, Sargeant LA, Williams KM, Prevost AT, Kinmonth AL, Wareham NJ, Griffin SJ . Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial. The Lancet 2012;380(9855):1741-8. PIs: Ann-Louise Kinmonth, Nick Wareham, Simon Griffin

    This research paper won the title of 2013 BMJ Awards Research Paper of the Year, and was awarded Diabetes Paper of the Year 2012 by the Royal College of Practitioners.

     

    Paddison CAM, Eborall HC, Sutton S, French DP, Vasconcelos J, Prevost AT, Kinmonth AL, Griffin SJ. Are people with negative diabetes screening tests falsely reassured?  A parallel group cohort study embedded in the ADDITION (Cambridge) randomised controlled trial. BMJ 2009;339:b4535. PI: Stephen Sutton

     

    Eborall HC, Griffin SJ, Prevost AT, Kinmonth AL, French DP, Sutton S. Psychological Impact of Screening for Type 2 Diabetes: Controlled Trial and Comparative Study Embedded in the ADDITION (Cambridge) Randomised Controlled trial. BMJ 2007;335:486. PI: Stephen Sutton

     

    Emery J, Morris H, Goodchild R, Fanshawe T, Prevost AT, Bobrow M, Kinmonth AL. The GRAIDS Trial: a cluster randomised controlled trial of computer decision support for the management of familial cancer risk in primary care. British Journal of Cancer 2007;97:486-493. CRUK funded. PI: Jon Emery.

     

    Cancer Diagnosis in Primary Care

     

    Walter FM, Morris HC, Humphrys E, Hall PN, Prevost AT, Burrows N, Bradshaw L, Wilson EC, Norris P, Walls J, Johnson M, Kinmonth AL, Emery JD. Effect of adding a diagnostic aid to best practice to manage suspicious pigmented lesions in primary care: randomised controlled trial. BMJ 2012;345:e4110

    This research paper was awarded Cancer Paper of the Year 2012 by the Royal College of Practitioners.

     

    Complex Intervention Trials, Fidelity of delivery, and Methods Research

     

    Kinmonth AL, Wareham NJ, Hardeman W, Sutton S, Prevost AT, Fanshawe T, Williams K, Ekelund U, Spiegelhalter D, Griffin SJ. Efficacy of a theory-based behavioural intervention to increase physical activity in an at-risk group in primary care (ProActive UK): a randomised trial. The Lancet 2008;371:41-48

     

    Lancaster GA, Campbell MJ, Eldridge S, Farrin A, Marchant M, Muller S, Perera R, Peters TJ, Prevost AT, Rait G. Trials in Primary Care: statistical  issues in the design, conduct and evaluation of complex interventions. Statistical Methods in Medical Research 2010;19:349-77

     

    Michie S, Hardeman W, Fanshawe T, Prevost AT, Taylor L, Kinmonth AL. Investigating theoretical explanations for behaviour change: The case study of ProActive. Psychology and Health 2008;23:25-39

     

    Hardeman W, Michie S, Fanshawe T, Prevost AT, Mcloughlin K, Kinmonth AL. Fidelity of delivery of a physical activity intervention: Predictors and consequences. Psychology and Health 2008;23:11-24

     

    Griffin SJ, Simmons RK, Prevost AT, Williams KM, Hardeman W, Sutton S, Brage S, Ekelund U, Parker RA, Wareham NJ, Kinmonth AL; on behalf of the ADDITION-Plus study team. Multiple behaviour change intervention and outcomes in recently diagnosed type 2 diabetes: the ADDITION-Plus randomised controlled trial. Diabetologia 2014;57:1308-19

     

    Trials involving psychology

     

    Hollands GJ, Whitwell SC, Parker RA, Prescott NJ, Forbes A, Sanderson J, Mathew CG, Lewis CM, Watts S, Sutton S, Armstrong D, Kinmonth AL, Prevost AT, Marteau TM. Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation: randomised controlled trial. BMJ 2012;345:e4708.


    Marteau TM, Mann E, Prevost AT, Vasconcelos JC, Kellar I, Sanderson S, Parker M, Griffin S, Sutton S, Kinmonth AL. Impact of an informed choice invitation on uptake of screening for diabetes in primary care (DICISION): a randomised trial. BMJ 2010;340:c2138

     

    Adaptive and staged studies

     

    TRIBUTE: Feasibility for Targeted Regulatory T Cell Therapy for Inflammatory Bowel Disease. Phase I/II Adaptive dose-finding trial. PI: Graham Lord (KCL) MRC DPFS funded

     

    An Open-label, Phase I/II Dose Escalation Trial of a Photoreceptor Transplantation in Adults with Cone Dystrophy. PI: Robin Ali (KCL). MRC DPFS

     

    Prevost AT. A journey from statistical consultation to funded adaptive trial.  Trials 2017;18(Suppl 1):P108

     

    Prevost AT, Bowden J. Designing a preliminary adaptive study to inform a biomarker trial in Psoriasis. Trials 2011;12(S1):A17

     

    Robertson D, Prevost AT, Bowden J. Accounting for selection and correlation in the analysis of two-stage genome-wide association studies. Biostatistics 2016 Oct;17(4):634-49

     

    Robertson D, Prevost AT, Bowden J. Unbiased estimation in seamless phase II/III trials with unequal treatment effect variances and hypothesis-driven selection rules. Statistics in Medicine 2016; Sep;35(22):3907-22

     

    Robertson D, Prevost AT, Bowden J. Correcting for bias in the selection and validation of informative diagnostic tests. Statistics in Medicine 2015 Apr 15;34(8):1417-37

     

    2nd PhD Supervisor of David Robertson

     

    Causal Mediation

     

    PhD Supervisor of Neil Casey

     

    Casey N, Thompson S, Prevost AT. Modelling multiple outcomes to improve the detection of causal mediation effects in complex intervention trials. Trials 2011;12(S1):O

     

    Application and Development of Meta-analysis methods in health research

     

    Prevost AT, Mason D, Griffin S, Kinmonth AL, Sutton S, Spiegelhalter D. Allowing for correlations between correlations in random-effects meta-analysis of correlation matrices. Psychological Methods 2007;12:434-50

     

    Vasconcelos J, Turner R, Prevost AT. Assessing the impact of an omitted study on the overall meta-analysis estimate. Trials 2017;18(Suppl 1):O60

     

    Naughton F, Prevost AT, Sutton S. Self-help smoking cessation interventions in pregnancy - a systematic review and meta-analysis. Addiction 2008;103:566-79

     

    Braithwaite D, Emery J, Walter F, Prevost AT, Sutton S. Psychological impact of genetic counseling for familial cancer: a systematic review and meta-analysis. Journal of the National Cancer Institute 2004;96:122-133.

     

    Clinical Trial research using Electronic Records

     

    2nd PhD Supervisor of Sena JAwad

     

    Jawad S, Modi N, Prevost AT, Gale C. A systematic review identifying common data items in neonatal trials and assessing their completeness in routinely recorded United Kingdom national neonatal data. Trials 2019;20:731. Imperial PhD studentship.

     

    Gulliford M, Prevost AT, Clegg A, Rezel-Potts E. Mortality of care home residents and community-dwelling controls during the COVID-19 pandemic in 2020: matched cohort study. J Am Med Dir Assoc. 2022 Jun;23(6):923-929.e2

     

    Gulliford MC, Prevost AT, Charlton J, Juszczyk D, Soames J, McDermott L, Sultana K, Wright M, Fox R, Hay A, Little P, Moore MV, Yardley L, Ashworth M. Effectiveness and safety of electronically-delivered prescribing feedback and decision support on antibiotic utilization for respiratory illness in primary care. BMJ 2019;364:I236. NIHR HTA funded.

     

     

    Imperial College London Collaborations

     

    iPREVENT: Increase colonic propionate as a method of preventing weight gain in young adults (RCT). PI: Gary Frost (Imperial) NIHR/MRC EME. Imperial CTU

     

    Rockall AG, Li X, Johnson N, Lavdas I, Santhakumaran S, Prevost AT, Punwani S, Goh V, Barwick T, Bharwani N, Sandhu A, Sidhu H, Plumb A, Burn J, Fagan A, Wengert GJ, Koh D-M, Reczko K, Qi S, Warwick J, Liu X, Messiou C, Tunariu N, Boavida P, Soneji N, Johnston EW, Kelly-Morland C, De Paepae K, Sokhi H, Wallitt K, Lakshani A, Russell J, Salib M, Vinnicombe S, Haq A, Aboagye E, Stuart T, Glocker B. Development and evaluation of machine learning in whole-body magnetic resonance imaging for detecting metastases in patients with lung or colon cancer: a diagnostic t. est accuracy study. Investigative Radiology 2023; June 26. Imperial CTU

     

    Tan T, Khoo B, Mills EG, Phylactou M, Patel B, Eng PC, Thurston L, Muzi B, Meeran K, Prevost AT, Comninos AN, Abbara A, Dhillo WS. Association between high serum total cortisol concentrations and mortality from COVID-19. Lancet Diabetes & Endocrinology 2020;8:659-60

     

    Santhakumaran S, Gordon A, Prevost AT, O'Kane C, McAuley DF, Shankar-Hari M. Heterogeneity of Treatment Effect by Baseline Risk of Mortality in Critically Ill Patients: Re-analysis of three recent Sepsis and ARDS Randomised Controlled Trials. Critical Care 2019;23(1):156. NIHR/MRC EME funded. Imperial CTU

     

    Kenkre JS, Ahmed AR, Purkayastha S, Malallah K, Bloom S, Blakemore A, Prevost AT, Tan T. Who will benefit from bariatric surgery for diabetes? A protocol for an observational cohort study. BMJ Open 2021 Feb 10;11(2):e042355. NIHR Doctoral Fellowship funded.

     

    Behary P, Tharakan G, Alexiadou K, Johnson N, Wewer Albrechtsen NJ, Kenkre J, Cuenco J, Hope D, Anyiam O, Choudhury S, Alessimii H, Poddar A, Minnion J, Doyle C, Frost G, Le Roux C, Purkayastha S,  Moorthy K, Dhillo W, Holst JJ, Ahmed AR, Prevost AT, Bloom SR, Tan TM. Combined GLP-1, oxyntomodulin and peptide YY improves body weight and glycaemia in obesity and prediabetes/type 2 diabetes: a randomized single-blinded placebo controlled study. Diabetes Care 2019;42(8):1446-53

     

    Cambridge (University and NHS Trust) Primary and Secondary Care Collaborations

     

    Hardeman W, Mitchell J, Pears S, Van Emmenis M, Theil F, GC VS, Vasconcelos JC, Westgate K, Brage S, Suhrcke M, Griffin S, Kinmonth AL, Wilson ECF, Prevost AT, Sutton S. Evaluation of a very brief pedometer-based physical activity intervention delivered in NHS Health Checks: The VBI randomised controlled trial. Plos Medicine 2020; Mar 6;17(3):e1003046. NIHR Programme Grants for Applied Research funded.

     

    Naughton F, Jamison J, Boase S, Sloan M, Gilbert H, Prevost AT, Mason D, Smith S, Brimicombe J, Evans R, Sutton S. Randomized controlled trial to assess the short-term effectiveness of tailored web- and text-based facilitation of smoking cessation in primary care (iQuit in Practice). Addiction 2014;109:1184-93. Cancer Research UK funded.

     

    Simmons RK, Echouffo-Tcheugui JB, Sharp SJ, Sargeant LA, Williams KM, Prevost AT, Kinmonth AL, Wareham NJ, Griffin SJ . Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial. The Lancet 2012;380(9855):1741-8 (role principally in the trial design and conduct stages) Wellcome Trust and NIHR funded.

     

    Walter FM, Morris HC, Humphrys E, Hall PN, Prevost AT, Burrows N, Bradshaw L, Wilson EC, Norris P, Walls J, Johnson M, Kinmonth AL, Emery JD. Effect of adding a diagnostic aid to best practice to manage suspicious pigmented lesions in primary care: randomised controlled trial. BMJ 2012;345:e4110. NIHR School for Primary Care Research funded.

     

    Corrie PG, Moody AM, Armstrong G, Nolasco S, Lao-Sirieix S-H, Bavister L, Prevost AT, Parker R, Sabes-Figuera R, McCrone P, Balsdon H, McKinnon K, Hounsell A, O’Sullivan B, Barclay S. Is community treatment best? A randomised trial comparing delivery of cancer treatment in the hospital, home and GP surgery. British Journal of Cancer 2013;109:1549-55. NIHR RfPB funded. NIHR Research for Patient Benefit funded.

     

    Hollands GJ, Whitwell SC, Parker RA, Prescott NJ, Forbes A, Sanderson J, Mathew CG, Lewis CM, Watts S, Sutton S, Armstrong D, Kinmonth AL, Prevost AT, Marteau TM. Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation: randomised controlled trial. BMJ 2012;345:e4708. Wellcome Trust funded.

     

    Kelly JD, Dudderidge TJ, Wollenschlaeger A, Okoturo O, Burling K, Tulloch F, Halsall I, Prevost T, Prevost AT, Vasconcelos JC, Robson W, Leung HY, Vasdev N, Pickard RS, Williams GH, Stoeber K. Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of mcm5 and nuclear matrix protein 22. PLoS One 2012;7:e40305. Cancer Research UK funded.

     

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    • SDG 3 - Good Health and Well-being

    Education/Academic qualification

    Social Statistics, Doctor of Philosophy, Multilevel Modelling of Child Mortality: Gibbs Sampling versus other approaches, University of Southampton

    1 Oct 199330 Sept 1996

    Award Date: 30 Sept 1996

    Statistics with Applications in Medicine, Master in Science, Summer Dissertation: Random Effect Models for Birth Interval Effects on Infant Mortality in Tunisia, University of Southampton

    1 Oct 199030 Sept 1991

    Award Date: 30 Sept 1991

    Mathematics with Statistics, Bachelor of Science, University of Southampton

    1 Oct 198630 Jun 1990

    Award Date: 30 Jun 1990

    External positions

    Expert Panel Member of NICE Rapid Guideline for Vitamin D and Covid-19, joint with SACN (the Scientific Advisory Committee on Nutrition)

    1 Nov 202031 Dec 2020

    NIHR COVID Call Committee for Recovery and Learning Research

    12 Jun 202031 Aug 2020

    Visiting Professor, Imperial College London

    1 Jun 20201 Jun 2023

    Honorary Senior Visiting Fellow, Palliative and End Of Life Care Group, University of Cambridge

    1 Jun 202031 Dec 2022

    NICE Centre for Guidelines Expert Advisor

    11 Oct 2017 → …

    NIHR Public Health Research Committee

    1 Jun 201417 Jun 2020

    NICE Public Health Advisory Committee

    7 Jun 201330 Jun 2020

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