Tony Pagliuca

2022

A national service for delivering CD19 CAR-Tin large B-cell lymphoma – The UK real-world experience

Kuhnl, A., Roddie, C., Kirkwood, A. A., Tholouli, E., Menne, T., Patel, A., Besley, C., Chaganti, S., Sanderson, R., O'Reilly, M., Norman, J., Osborne, W., Bloor, A., Lugthart, S., Malladi, R., Patten, P. E. M., Neill, L., Martinez-Cibrian, N., Kennedy, H., Phillips, E. H., & 17 othersJones, C., Sharplin, K., El-Sharkawi, D., Latif, A. L., Mathew, A., Uttenthal, B., Stewart, O., Marzolini, M. A. V., Townsend, W., Cwynarski, K., Ardeshna, K., Ardavan, A., Robinson, K., Pagliuca, A., Collins, G. P., Johnson, R. & McMillan, A., Aug 2022, In: British Journal of Haematology. 198, 3, p. 492-502 11 p.

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

UCART19, a first-in-class allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia (CALM): a phase 1, dose-escalation trial

CALM Study Group, Nov 2022, In: The Lancet Haematology. 9, 11, p. e833-e843

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

2021

Risk of COVID-19 death in cancer patients: an analysis from Guy's Cancer Centre and King's College Hospital in London

Guy’s Cancer Real World Evidence, 28 Sept 2021, In: British journal of cancer. 125, 7, p. 939-947 9 p.

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

2020

Early and late-onset veno-occlusive disease/sinusoidal syndrome post allogeneic stem cell transplantation – a real-world UK experience

Mehra, V., Tetlow, S., Choy, A., de Lavallade, H., Kulasekararaj, A., Krishnamurthy, P., Avenoso, D., Marsh, J., Potter, V., Mufti, G., Pagliuca, A. & Gandhi, S., 2020, (Accepted/In press) In: American Journal of Transplantation.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies

UCART19 Group, 12 Dec 2020, In: The Lancet. 396, 10266, p. 1885-1894 10 p.

Research output: Contribution to journal › Article › peer-review

225 Citations (Scopus)

2019

Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study

Kizilors, A., Crisà, E., Lea, N., Passera, R., Mian, S., Anwar, J., Best, S., Nicolini, F. E., Ireland, R., Aldouri, M., Pocock, C., Corbett, T., Gale, R., Bart-Smith, E., Weston-Smith, S., Wykes, C., Kulasekararaj, A., Jackson, S., Harrington, P., McLornan, D., & 4 othersRaj, K., Pagliuca, A., Mufti, G. J. & de Lavallade, H., May 2019, In: The Lancet Haematology. 6, 5, p. e276-e284

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Epstein-Barr Virus and Monoclonal Gammopathy of Clinical Significance in Autologous Stem Cell Transplantation for Multiple Sclerosis

Mehra, V., Rhone, E., Widya, S., Zuckerman, M., Potter, V., Raj, K., Kulasekararaj, A. G., McLornan, D. P., de Lavallade, H., Benson-Quarm, N., Lim, C., Ware, S., Sudhanva, M., Malik, O., Nicholas, R., Muraro, P. A., Marsh, J., Mufti, G. J., Silber, E., Pagliuca, A., & 1 othersKazmi, M., 30 Oct 2019, In: Clinical Infectious Diseases. 69, 10, p. 1757-1763 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

19 Citations (Scopus)

404 Downloads (Pure)

Full donor chimerism without graft-versus-host disease: the key factor for maximum benefit of pre-emptive donor lymphocyte infusions (pDLI)

Feliu, J., Potter, V., Grimaldi, F., Clay, J., Floro, L., Saha, C., Barber, L., Orti, G., Alnagar, A. A. R., Garcia-Muñoz, R., Kenyon, M., Krishnamurthy, P., de Lavallade, H., Raj, K., McLornan, D., Pagliuca, A. & Mufti, G. J., 26 Sept 2019, (E-pub ahead of print) In: Bone Marrow Transplantation.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Mesenchymal stromal cells for acute graft‐versus‐host disease: response at 1 week predicts probability of survival

Galleu, A., Milojkovic, D., Deplano, S., Szydlo, R., Loaiza, S., Wynn, R., Marks, D. I., Richardson, D., Orchard, K., Kanfer, E., Tholouli, E., Saif, M., Sivaprakasam, P., Lawson, S., Bloor, A., Pagliuca, A., Potter, V., Mehra, V., Snowden, J. A., Vora, A., & 4 othersKishore, B., Hunter, H., Apperley, J. F. & Dazzi, F., Apr 2019, In: British Journal of Haematology. 185, 1, p. 89-92 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

29 Citations (Scopus)

108 Downloads (Pure)

Similar outcomes of alemtuzumab-based hematopoietic cell transplantation for SAA patients older or younger than 50 years

Sheth, V. S., Potter, V., Gandhi, S. A., Kulasekararaj, A. G., de Lavallade, H., Muus, P., Pagliuca, A., Rice, C. F. M., Mehra, V., Grimaldi, F., Inam, S., Barber, L. D., Mufti, G. J. & Marsh, J. C., 22 Oct 2019, In: Blood Advances. 3, 20, p. 3070-3079 10 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

2018

Cancer immunotherapy with CAR-T cells - Behold the future

Graham, C., Hewitson, R., Pagliuca, A. & Benjamin, R., 1 Aug 2018, In: Clinical Medicine, Journal of the Royal College of Physicians of London. 18, 4, p. 324-328 5 p.

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

2017

Composite biomarker panel for prediction of severity and diagnosis of acute GVHD with T-cell-depleted allogeneic stem cell transplants - single centre pilot study

Min, S. S., Mehra, V., Clay, J., Cross, G. F., Douiri, A., Dew, T., Basu, T. N., Potter, V., Ceesay, M. M., Pagliuca, A., Sherwood, R. A. & Vincent, R. P., Oct 2017, In: Journal of Clinical Pathology. 70, 10, p. 886-890

Research output: Contribution to journal › Article › peer-review

Open Access

File

14 Citations (Scopus)

339 Downloads (Pure)

Mixed T-Cell Chimerism after Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia Using an Alemtuzumab-Containing Regimen is Shaped by Persistence of Recipient CD8 T Cells

Grimaldi, F., Potter, V., Perez-Abellan, P., Veluchamy, J. P., Atif, M., Grain, R., Sen, M., Best, S., Lea, N., Rice, C., Pagliuca, A., Mufti, G. J., Marsh, J. C. W. & Barber, L. D., 1 Feb 2017, In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 23, 2, p. 293-299

Research output: Contribution to journal › Article › peer-review

Open Access

File

28 Citations (Scopus)

494 Downloads (Pure)

2016

Baseline Cytokine profiling identifies novel risk factors for invasive fungal disease among haematology patients undergoing intensive chemotherapy or haematopoietic stem cell transplantation

Ceesay, M. M., Kordasti, S., Rufaie, E., Lea, N., Smith, M., Wade, J., Douiri, A., Mufti, G. J. & Pagliuca, A., Sept 2016, In: Journal of Infection. 73, 3, p. 280-288 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

210 Downloads (Pure)

Composite Biomarker Panel in Prediction of Severity and Diagnosis of Acute GvHD with T- Depleted Allogeneic Stem Cell Transplants: Single Centre Pilot Study

Min, S. S., Mehra, V., Clay, J., Cross, G., Douiri, A., Dew, T., Potter, V. T., Basu, T., Sherwood, R., Vincent, R., Ceesay, M. M. & Pagliuca, A., 2 Dec 2016, In: Blood. 128, 22, p. 2234

Research output: Contribution to journal › Article › peer-review

Low Incidence of Hemolysis, Delayed Red Cell Engraftment and Pure Red Cell Aplasia with Post Transplantation Cyclophosphamide following ABO Mismatched Non-Myeloablative Haploidentical Peripheral Blood Stem Cell Transplantation: Abstracts from the 2016 BMT Tandem Meetings

Fasan, O., O'Donnell, P. V., Pagliuca, A., Copelan, E. A. & Raj, K., 18 Mar 2016, (E-pub ahead of print) In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 22, 3, Supplement, p. S318-S319

Research output: Contribution to journal › Article › peer-review

2015

Impact of ATG-containing reduced-intensity conditioning after single- or double-unit allogeneic cord blood transplantation

Pascal, L., Tucunduva, L., Ruggeri, A., Blaise, D., Ceballos, P., Chevallier, P., Cornelissen, J., Maillard, N., Tabrizi, R., Petersen, E., Linkesch, W., Sengeloev, H., Kenzey, C., Pagliuca, A., Holler, E., Einsele, H., Gluckman, E., Rocha, V., Yakoub-Agha, I., Eurocord, & 1 othersEuropean Society for Blood, S. F. B., 20 Aug 2015, In: Blood. 126, 8, p. 1027-1032 6 p.

Research output: Contribution to journal › Article › peer-review

72 Citations (Scopus)

2014

Impact of extracorporeal photopheresis on skin scores and quality of life in patients with steroid-refractory chronic GVHD

Dignan, F. L., Aguilar, S., Scarisbrick, J. J., Shaw, B. E., Potter, M. N., Cavenagh, J., Apperley, J. F., Fielding, A. K., Pagliuca, T., Raj, K., Marks, D. I., Peniket, A., Crawley, C., Koh, M. B. & Child, F. J., May 2014, In: Bone Marrow Transplantation. 49, 5, p. 704-708 5 p.

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Long term follow-up of BEAM-autologous and BEAM-alemtuzumab allogeneic stem cell transplantation in relapsed advanced stage follicular lymphoma

Noriega, V., Kaur, H., Devereux, S., Byrne, J., Marcus, R., Haynes, A., Yallop, D., McMillan, A., Ingram, W., Khan, A., Kenyon, M., Potter, V., Russell, N., Mufti, G. J. & Pagliuca, A., Jul 2014, In: Leukemia Research. 38, 7, p. 737-743 7 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Long-Term Outcomes of Alemtuzumab-Based Reduced-Intensity Conditioned Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome and Acute Myelogenous Leukemia Secondary to Myelodysplastic Syndrome

Potter, V. T., Krishnamurthy, P., Barber, L. D., Lim, Z., Kenyon, M., Ireland, R. M., de Lavallade, H., Dhouri, A., Marsh, J. C. W., Marcus, R., Devereux, S., Ho, A., Pagliuca, T. & Mufti, G. J., Jan 2014, In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 20, 1, p. 111-117 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

22 Citations (Scopus)

93 Downloads (Pure)

Nonmyeloablative Peripheral Blood Haploidentical Stem Cell Transplantation for Refractory Severe Aplastic Anemia

Clay, J., Kulasekararaj, A. G., Potter, V., Grimaldi, F., McLornan, D., Raj, K., de Lavallade, H., Kenyon, M., Pagliuca, T., Mufti, G. & Marsh, J. C. W., Nov 2014, In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 20, 11, p. 1711-1716 6 p.

Research output: Contribution to journal › Article › peer-review

105 Citations (Scopus)

Retrospective study of alemtuzumab vs ATG-based conditioning without irradiation for unrelated and matched sibling donor transplants in acquired severe aplastic anemia: a study from the British Society for Blood and Marrow Transplantation

Marsh, J. C., Pearce, R. M., Koh, M. B. C., Lim, Z., Pagliuca, A., Mufti, G. J., Perry, J., Snowden, J. A., Vora, A. J., Wynn, R. T., Russell, N., Gibson, B., Gilleece, M., Milligan, D., Veys, P., Samarasinghe, S., McMullin, M., Kirkland, K., Cook, G. & British Soc Blood Marrow, Jan 2014, In: Bone Marrow Transplantation. 49, 1, p. 42-48 7 p.

Research output: Contribution to journal › Article › peer-review

72 Citations (Scopus)

2013

BCSH/BSBMT guideline: diagnosis and management of veno-occlusive disease (sinusoidal obstruction syndrome) following haematopoietic stem cell transplantation

Dignan, F. L., Wynn, R. F., Hadzic, N., Karani, J., Quaglia, A., Pagliuca, T., Veys, P., Potter, M. N., Haemato-oncology Task Force & British Soc Blood Marrow, Nov 2013, In: British Journal of Haematology. 163, 4, p. 444-457 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

245 Citations (Scopus)

2012

Plerixafor for PBSC mobilisation in myeloma patients with advanced renal failure: safety and efficacy data in a series of 21 patients from Europe and the USA

Douglas, K. W., Parker, A. N., Hayden, P. J., Rahemtulla, A., D'Addio, A., Lemoli, R. M., Rao, K., Maris, M., Pagliuca, T., Uberti, J., Scheid, C., Noppeney, R., Cook, G., Bokhari, S. W., Worel, N., Mikala, G., Masszi, T., Taylor, R. & Treisman, J., Jan 2012, In: Bone Marrow Transplantation. 47, 1, p. 18-23 6 p.

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

Glotz, D., Chapman, J. R., Dharnidharka, V. R., Hanto, D. W., Castro, M. C. R., Hirsch, H. H., Leblond, V., Mehta, A. K., Moulin, B., Pagliuca, A., Pascual, J., Rickinson, A. B., Russo, F. P., Trappe, R. U., Webster, A. C., Zuckermann, A. O. & Gross, T. G., 27 Oct 2012, In: Transplantation. 94, 8, p. 784-793 10 p.

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

2011

Alemtuzumab based reduced intensity conditioning allogeneic haematopoietic stem cell transplantation for myelofibrosis

Nagi, W., Lim, Z. Y., Krishnamurthy, P., Potter, V., Tindell, V., Reiff-Zall, L., Abdullah, A., Lea, N., Kenyon, M., Marsh, J., Ho, A. Y. L., Mufti, G. J. & Pagliuca, T., Aug 2011, In: Leukemia Research. 35, 8, p. 998 - 1000 3 p.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Alemtuzumab with fludarabine and cyclophosphamide reduces chronic graft-versus-host disease after allogeneic stem cell transplantation for acquired aplastic anemia

Marsh, J., Gupta, V., Lim, Z., Ho, A. Y., Ireland, R., Hayden, J., Potter, V., Koh, M. B., Islam, M. S., Russell, N., Marks, D. I., Mufti, G. J. & Pagliuca, T., 25 Aug 2011, In: Blood. 118, 8, p. 2351 - 2357 7 p.

Research output: Contribution to journal › Article › peer-review

136 Citations (Scopus)

Measurement of Posaconazole, Itraconazole, and Hydroxyitraconazole in Plasma/Serum by High-Performance Liquid Chromatography With Fluorescence Detection

Buckner, S. L., Ceesay, M. M., Pagliuca, T., Morgan, P. & Flanagan, B., Dec 2011, In: Therapeutic Drug Monitoring. 33, 6, p. 735-741 7 p.

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

The outcome of high-dose chemotherapy and auto-SCT in patients with multiple myeloma: a UK/Ireland and European benchmarking comparative analysis

Cook, G., Jackson, G. H., Morgan, G. J., Russell, N., Kirkland, K., Lee, J., Pearce, R., Marks, D. I. & Pagliuca, T., Sept 2011, In: Bone Marrow Transplantation. 46, 9, p. 1210 - 1218 9 p.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Use of Zidovudine and Interferon Alfa With Chemotherapy Improves Survival in Both Acute and Lymphoma Subtypes of Adult T-Cell Leukemia/Lymphoma

Hodson, A., Crichton, S., Montoto, S., Mir, N., Matutes, E., Cwynarski, K., Kumaran, T., Ardeshna, K. M., Pagliuca, T., Taylor, G. P. & Fields, P., 10 Dec 2011, In: Journal of Clinical Oncology. 29, 35, p. 4696 - 4701 6 p.

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Voriconazole versus itraconazole for antifungal prophylaxis following allogeneic haematopoietic stem-cell transplantation

Marks, D. I., Pagliuca, T., Kibbler, C. C., Glasmacher, A., Heussel, C-P., Kantecki, M., Miller, P. J. S., Ribaud, P., Schlamm, H. T., Solano, C., Cook, G. & IMPROVIT Study Grp, Nov 2011, In: British Journal of Haematology. 155, 3, p. 318-327 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

198 Citations (Scopus)

2010

The prevalence of the activating JAK2 tyrosine kinase mutation in chronic porto-splenomesenteric venous thrombosis

Orr, D. W., Patel, R. K., Lea, N. C., Westbrook, R., O'Grady, J. G., Heaton, N. D., Pagliuca, T., Mufti, G. J. & Heneghan, M. A., Jun 2010, In: Alimentary Pharmacology and Therapeutics. 31, 12, p. 1330 - 1336 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Citations (Scopus)

1997

The clinical diversity and role of chemotherapy in lymphoproliferafive disorder in liver transplant recipients

McCarthy, M., Ramage, J., McNair, A., Gane, E., Portmann, B., Pagliuca, A., Rela, M., Heaton, N., Mufti, G. J. & Williams, R., Dec 1997, In: Journal of Hepatology. 27, 6, p. 1015-1021 7 p.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Tony Pagliuca

Research output

Search results