King's College London

Research portal

Dr Wendy Noble

  1. Tau in the gut, does it really matter?

    Derkinderen, P., Rolli-Derkinderen, M., Chapelet, G., Neunlist, M. & Noble, W., Jul 2021, In: Journal of Neurochemistry. 158, 2, p. 94-104 11 p.

    Research output: Contribution to journalReview articlepeer-review

  2. Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2

    Staurenghi, E., Cerrato, V., Gamba, P., Testa, G., Giannelli, S., Leoni, V., Caccia, C., Buffo, A., Noble, W., Perez-Nievas, B. G. & Leonarduzzi, G., Feb 2021, In: Redox Biology. 39, 101837.

    Research output: Contribution to journalArticlepeer-review

  3. Oxysterols present in Alzheimer’s disease brain induce synaptotoxicity by activating astrocytes: a major role for lipocalin-2

    Staurenghi, E., Cerrato, V., Gamba, P., Testa, G., Giannelli, S., Leoni, V., Caccia, C., Buffo, A., Noble, W., Gomez Perez-Nievas, B. & Leonarduzzi, G., 15 Dec 2020, (Accepted/In press) In: Redox Biology.

    Research output: Contribution to journalArticlepeer-review

  4. Upregulation of enteric alpha-synuclein as a possible link between inflammatory bowel disease and Parkinson’s disease

    Derkinderen, P., Noble, W., Neunlist, M. & Rolli-Derkinderen, M., 17 Nov 2020, In: Gut. gutjnl-2020-323482.

    Research output: Contribution to journalLetterpeer-review

  5. Astrocytes in Tauopathies

    Reid, M., Beltran Lobo, P., Johnson, L., Gomez Perez-Nievas, B. & Noble, W., 24 Sep 2020, In: Frontiers in Neurology. 11, 572850.

    Research output: Contribution to journalReview articlepeer-review

  6. Enteric synucleinopathy: from trendy concept to real entity

    de Guilhem de Lataillade, A., Lebouvier, T., Laclair-Visonneau, L., Noble, W. & Derkinderen, P., 23 Aug 2020, In: Free Neuropathology. 1, 1, p. 1-9 10 p., 1:28.

    Research output: Contribution to journalReview articlepeer-review

  7. Tau accumulates in Crohn's disease gut

    Prigent, A., Chapelet, G., de Guilhem de Lataillade, A., Oullier, T., Durieu, E., Bourreille, A., Duchalais, E., Hardonniere, K., Neunlist, M., Noble, W., Kerdine-Romer, S., Derkinderen, P. & Rolli-Derkinderen, M., 1 Jul 2020, In: THE FASEB JOURNAL : OFFICIAL PUBLICATION OF THE FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY. 34, 7, p. 9285-9296 12 p.

    Research output: Contribution to journalArticlepeer-review

  8. Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer’s disease: the MADE Phase II, three-arm RCT

    Howard, R., Zubko, O., Gray, R., Bradley, R., Harper, E., Kelly, L., Pank, L., O'Brien, J., Fox, C., Tabet, N., Livingston, G., Bentham, P., McShane, R., Burns, A., Ritchie, C., Reeves, S., Lovestone, S., Ballard, C., Noble, W., Wilcock, G. & 1 others, Nilforooshan, R., 20 Apr 2020, In: Efficacy and Mechanism Evaluation. 7, 2, p. 1-45 46 p., 7(2).

    Research output: Contribution to journalArticlepeer-review

  9. Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A randomized clinical trial

    Howard, R. J., Zubko, O., Bradley, R., Harper, E., Kelly, L., Pank, L., O'Brien, J. T., Fox, C., Tabet, N., Livingstone, G., Bentham, P., McShane, R., Burns, A., Ritchie, C., Reeves, S., Lovestone, S., Ballard, C., Noble, W., Nilforooshan, R., Wilcock, G. & 1 others, Gray, R., 1 Feb 2020, In: JAMA Neurology. 77, 2, p. 164-174

    Research output: Contribution to journalArticlepeer-review

  10. Upregulation of enteric alpha-synuclein as a possible link between inflammatory bowel disease and Parkinson's disease

    Derkinderen, P., Noble, W., Neunlist, M. & Rolli-Derkinderen, M., 2020, (Accepted/In press) In: Gut. gutjnl-2020-323482.

    Research output: Contribution to journalLetterpeer-review

  11. Considerations for future tau-targeted therapeutics: can they deliver?

    Noble, W., Jimenez-Sanchez, M., Perez-Nievas, B. G. & Hanger, D. P., 29 Oct 2019, In: Expert Opinion On Drug Discovery. 3 p.

    Research output: Contribution to journalEditorialpeer-review

  12. Tackling gaps in developing life-changing treatments for dementia

    Benn, C., Davis, J., Dawson, G., Dawson, L., Evans, A., Fox, N., Gallacher, J., Hutton, M., Isaac, J., Jones, D., Jones, L., Lalli, G., Libri, V., Lovestone, S., Mauricio, R., Moody, C., Noble, W. J., Perry, V. H., Pickett, J. A., Reynolds, D. & 9 others, Ritchie, C., Rohrer, J., Routledge, C., Rowe, J., Snyder, H. M., Spires-Jones, T., Swartz, J., Truyen, L. & Whiting, P., 24 Jun 2019, In: Alzheimer's & Dementia. 5, p. 241-253 13 p.

    Research output: Contribution to journalReview articlepeer-review

  13. Ammon’s Horn 2 (CA2) of the Hippocampus: A Long-Known Region with a New Potential Role in Neurodegeneration

    Pang, C. C. C., Kiecker, C., O’Brien, J. T., Noble, W. & Chang, R. C. C., 1 Apr 2019, In: Neuroscientist. 25, 2, p. 167-180

    Research output: Contribution to journalArticlepeer-review

  14. Sleep well to slow Alzheimer's progression?

    Noble, W. J. & Spires-Jones, T., 22 Feb 2019, In: Science. 363, 6429, p. 813-814 2 p.

    Research output: Contribution to journalReview articlepeer-review

  15. Synaptic Localisation of Tau

    Hanger, D. P., Goniotaki, D. & Noble, W., 1 Jan 2019, Advances in Experimental Medicine and Biology. SPRINGER, p. 105-112 8 p. (Advances in Experimental Medicine and Biology; vol. 1184).

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  16. Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy

    Lionnet, A., Wade, M. A. J., Corbille, A-G., Prigent, A., Paillusson, S., Tasselli, M., Gonzales, J., Durieu, E., Derkinderen, M., Coron, E., Duchalais, E., Neunlist, M., Perkinton, M. S., Hanger, D. P., Derkinderen, P. & Noble, W. J., 24 Jul 2018, In: Acta Neuropathologica Communications. 6, 1, p. 1-17

    Research output: Contribution to journalArticlepeer-review

  17. Preparation of organotypic brain slice cultures for the study of Alzheimer’s disease

    Croft, C. L. & Noble, W. J., 15 May 2018, In: F1000Research.

    Research output: Contribution to journalArticlepeer-review

  18. A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies

    Giacomini, C., Koo, C. Y., Yankova, N., Tavares, I. A. F., Wray, S., Noble, W. J., Hanger, D. P. & Morris, J. D. H., 7 May 2018, In: Acta Neuropathologica Communications. 6, 37, p. 1-16 16 p., Acta Neuropathologica Communications 2018 6:37.

    Research output: Contribution to journalArticlepeer-review

  19. Preparation of organotypic brain slice cultures for the study of Alzheimer's disease

    Croft, C. L. & Noble, W., 1 Jan 2018, In: F1000Research. 7, 1 p.

    Research output: Contribution to journalArticlepeer-review

  20. FUNCTIONAL ROLES FOR TAOK KINASES IN THE DEVELOPMENT OF TAU PATHOLOGY IN ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Giacomini, C., Noble, W., Hanger, D. P. & Morris, J. DH., 20 Oct 2017, In: Alzheimer's & Dementia. 13, 7, Supplement, p. P328-P329

    Research output: Contribution to journalPoster abstractpeer-review

  21. Roles of tau protein in health and disease

    Guo, T., Noble, W. J. & Hanger, D. P., May 2017, In: Acta Neuropathologica. 133, 5, p. 665–704

    Research output: Contribution to journalReview articlepeer-review

  22. α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

    Paillusson, S., Gomez Suaga, P., Stoica, R., Little, D., Gissen, P., Devine, M. J., Noble, W., Hanger, D. P. & Miller, C. C. J., 23 Mar 2017, In: Acta Neuropathologica. 134, p. 129–149 21 p.

    Research output: Contribution to journalArticlepeer-review

  23. Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease: Keap1 as a therapeutic target for Alzheimer's Disease

    Kerr, F., Sofola-Adesakin, O., Ivanov, D., Gatliff, J., Gomez Perez-Nievas, B., Bertrand, H., Martinez, P., Callard, R., Snoeren, I., Cocheme, H., Adcott, J., Khericha, M., Castillo-Quan, J., Noble, W., Wells, G., Thornton, J. & Partridge, L., 2 Mar 2017, In: PL o S Genetics. 13, 3, 30 p., e1006593.

    Research output: Contribution to journalArticlepeer-review

  24. The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

    Gomez-Suaga, P., Paillusson, S., Stoica, R., Noble, W., Hanger, D. P. & Miller, C. C. J., 6 Feb 2017, In: Current Biology. 27, 3, p. 371-385 15 p.

    Research output: Contribution to journalArticlepeer-review

  25. Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate

    Bondulich, M. K., Guo, T., Meehan, C., Manion, J., Rodriguez-Martin, T., Mitchell, J. C., Hortobagyi, T., Yankova, N., Stygelbout, V., Brion, J-P., Noble, W. J. & Hanger, D. P., Aug 2016, In: Brain. 139, 8, p. 2290-2306 17 p.

    Research output: Contribution to journalArticlepeer-review

  26. Astrocytes and neuroinflammation in Alzheimer's disease

    Phillips, E. C., Croft, C. L., Kurbatskaya, K., O'Neill, M. J., Hutton, M. L., Hanger, D. P., Garwood, C. J. & Noble, W., 1 Oct 2014, In: Biochemical Society Transactions. 42, 5, p. 1321-1325 5 p.

    Research output: Contribution to journalArticlepeer-review

  27. A role for tau at the synapse in Alzheimer's disease pathogenesis

    Pooler, A. M., Noble, W. & Hanger, D. P., 1 Jan 2014, In: Neuropharmacology. 76 , Pt A, p. 1-8 8 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  28. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

    Killick, R., Ribe, E. M., Al-Shawi, R., Malik, B., Hooper, C., Fernandes, C., Dobson, R., Nolan, P. M., Lourdusamy, A., Furney, S., Lin, K., Breen, G., Wroe, R., To, A. W. M., Leroy, K., Causevic, M., Usardi, A., Robinson, M., Noble, W., Williamson, R. & 9 others, Lunnon, K., Kellie, S., Reynolds, C. H., Bazenet, C., Hodges, A., Brion, J-P., Stephenson, J., Paul Simons, J. & Lovestone, S., 1 Jan 2014, In: Molecular Psychiatry. 19, 1, p. 88-98 11 p.

    Research output: Contribution to journalArticlepeer-review

  29. Intracellular and Extracellular Roles for Tau in Neurodegenerative Disease

    Hanger, D. P., Lau, D. H. W., Phillips, E. C., Bondulich, M. K., Guo, T., Woodward, B. W., Pooler, A. M. & Noble, W., 2014, In: Journal of Alzheimer's disease : JAD. 40, Supplement 1, p. S37-S45 9 p.

    Research output: Contribution to journalArticlepeer-review

  30. Tau phosphorylation affects its axonal transport and degradation

    Rodríguez-Martín, T., Cuchillo-Ibáñez, I., Noble, W., Nyenya, F., Anderton, B. H. & Hanger, D. P., Sep 2013, In: Neurobiology of Aging. 34, 9, p. 2146-2157 12 p.

    Research output: Contribution to journalArticlepeer-review

  31. The importance of tau phosphorylation for neurodegenerative diseases

    Noble, W., Hanger, D., Miller, C. & Lovestone, S., 1 Jul 2013, In: Frontiers in Neurology. 4, 83

    Research output: Contribution to journalBook/Film/Article reviewpeer-review

Previous 1 2 Next

Export:RIS BibTex Word PDF - will at most contain 500 items

Search within the list

Refine results

Language

Language

Publication year

Publication year

Meeting and poster abstracts

Meeting and poster abstracts

Open Access Status

Open Access Status

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454