Wendy Noble

Active

Structural and functional studies of the VAPB-PTPIP51 ER-mitochondria tethering proteins in neurodegenerative diseases

Miller, C. (Primary Investigator), Atherton, J. (Co-Investigator), Mitchell, J. (Co-Investigator), Noble, W. (Co-Investigator) & Vagnoni, A. (Co-Investigator)

MRC Medical Research Council

30/10/2023 → 29/10/2026

Project: Research

Investigating the crosstalk between autophagy and inflammation in astrocytes in Alzheimer's disease

Jimenez Sanchez, M. (Primary Investigator), Gomez Perez-Nievas, B. (Co-Investigator), Noble, W. (Co-Investigator) & Yang, F. (Co-Investigator)

Alzheimer's Research UK

6/09/2021 → 7/05/2025

Project: Research

Finished

Alzheimer’s Research UK King’s College London Network Centre Grant

Bateman, J. (Primary Investigator), Aarsland, D. (Co-Investigator), Cash, D. (Co-Investigator), Fanto, M. (Co-Investigator), Giese, P. (Co-Investigator), Hanger, D. (Co-Investigator), Hirth, F. (Co-Investigator), Malcangio, M. (Co-Investigator), Miller, C. (Co-Investigator), Mitchell, J. (Co-Investigator), Mondal, M. (Co-Investigator), Noble, W. (Co-Investigator), Parsons, R. (Co-Investigator), Ruepp, M.-D. (Co-Investigator), Serrano Navacerrada, M. E. (Co-Investigator), So, P.-W. (Co-Investigator), Sreedharan, J. (Co-Investigator), Troakes, C. (Co-Investigator), Vagnoni, A. (Co-Investigator), Vance, C. (Co-Investigator), Vernon, A. (Co-Investigator) & academic, A. (Co-Investigator)

Alzheimer's Research UK

1/09/2020 → 30/09/2022

Project: Research

Functional role of presynaptic tau during aging

Noble, W. (Primary Investigator) & Giese, P. (Co-Investigator)

AstraZeneca UK Ltd

1/10/2019 → 30/09/2023

Project: Research

Studying alterations in tau release during tauopathy development

Noble, W. (Primary Investigator), Hanger, D. (Co-Investigator) & Gomez Perez-Nievas, B. (Co-Investigator)

Alzheimer's Research UK

1/10/2019 → 22/03/2024

Project: Research

Endoplasmic reticulum (ER)-mitochondria signaling as a new therapeutic target for dementia.

Miller, C. (Primary Investigator), Noble, W. (Co-Investigator), Mitchell, J. (Co-Investigator) & Vagnoni, A. (Co-Investigator)

Alzheimer's Research UK

1/08/2019 → 31/08/2024

Project: Research

Investigating the effects of tau on lysosomes in the development of dementia

Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)

Alzheimer's Society

1/07/2019 → 1/04/2023

Project: Research

Investigating P2X7-mediated inflammatory signalling in Alzheimer’s Disease

Noble, W. (Primary Investigator) & Gomez Perez-Nievas, B. (Co-Investigator)

Alzheimer's Research UK

1/10/2018 → 30/06/2022

Project: Research

Biological Resource Analysis to Identify New MEchanisms and phenotypes in Neurodegenerative Diseases

Al-Chalabi, A. (Primary Investigator), Breen, G. (Co-Investigator), Ray Chaudhuri, K. (Co-Investigator), Noble, W. (Co-Investigator) & Aarsland, D. (Co-Investigator)

MRC Medical Research Council

1/02/2018 → 31/01/2021

Project: Research

Understanding neuronal cell death in dementia

Fanto, M. (Primary Investigator), Hanger, D. (Primary Investigator) & Noble, W. (Primary Investigator)

Alzheimer's Research UK

1/01/2018 → 30/06/2018

Project: Research

Investigating the importance of tau in the enteric nervous system for the propagation of tau pathology in Alzheimer's disease

Noble, W. (Primary Investigator), Hanger, D. (Co-Investigator) & Paillusson, S. (Co-Investigator)

1/10/2017 → 30/09/2020

Project: Research

Investigating the role of astrocytic REST in dementia

Hanger, D. (Primary Investigator), Noble, W. (Co-Investigator) & academic, A. (Co-Investigator)

1/10/2017 → 30/09/2021

Project: Research

Alzheimer’s Research UK King’s College London Network Centre

Hanger, D. (Primary Investigator), Miller, C. (Co-Investigator), Noble, W. (Co-Investigator), Giese, P. (Co-Investigator), Hirth, F. (Co-Investigator), Parsons, R. (Co-Investigator) & Bateman, J. (Co-Investigator)

Alzheimer's Research UK

1/09/2017 → 28/02/2022

Project: Research

Using a novel model of disease to understand mechanisms underlying the development of human tauopathy

Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)

Alzheimer's Society

1/02/2017 → 31/01/2020

Project: Research

A Neurinflammation Research Cluster at King's College London

Shaw, C. (Primary Investigator), Noble, W. (Co-Investigator), Politis, M. (Co-Investigator) & Taams, L. (Co-Investigator)

MRC Medical Research Council

12/12/2016 → 11/12/2019

Project: Research

Refining a new mouse model of tauopathy

Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)

Alzheimer's Research UK

14/11/2016 → 13/04/2017

Project: Research

Correcting defective endoplasmic reticulum-mitochondria associations as a new therapeutic target for fronto-temporal dementia

Miller, C. (Primary Investigator), Noble, W. (Co-Investigator) & Paillusson, S. (Co-Investigator)

Alzheimer's Society

1/10/2016 → 31/12/2021

Project: Research

ARUK Network Centre

Hanger, D. (Primary Investigator), Miller, C. (Primary Investigator), Francis, P. (Co-Investigator), Giese, P. (Co-Investigator), Hirth, F. (Co-Investigator), Noble, W. (Co-Investigator) & Parsons, R. (Co-Investigator)

Alzheimer's Research UK

1/09/2016 → 31/08/2017

Project: Research

Astrocyte-neuron communication in Alzheimer's disease: the role of extracellular chaperones

Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)

1/07/2016 → 3/06/2020

Project: Research

Astrocyte-secreted chaperones as a non-cell autonomous form of neuronal protection in Alzheimer's disease

Hanger, D. (Primary Investigator), Jimenez Sanchez, M. (Primary Investigator) & Noble, W. (Primary Investigator)

MRC Medical Research Council

1/07/2016 → 4/09/2021

Project: Research

Investigating the role of BIN1 in tau missorting and secretion

Glennon, E. (Primary Investigator) & Noble, W. (Co-Investigator)

Alzheimer's Research UK

1/06/2016 → 31/05/2019

Project: Research

Astrocyte-secreted chaperones as a non-cell autonomous form of neuronal protection in Alzheimer's disease

Hanger, D. (Primary Investigator), Jimenez Sanchez, M. (Primary Investigator) & Noble, W. (Primary Investigator)

1/06/2016 → 31/05/2020

Project: Research

The effect of BIN1 and amyloid-beta oligomers on missorting and spread of tau

Glennon, E. (Primary Investigator) & Noble, W. (Co-Investigator)

1/01/2016 → 31/12/2018

Project: Research

A Novel Strategy to Prevent Neurodegeneration in Alzheimer's Disease

Giese, P. (Primary Investigator) & Noble, W. (Co-Investigator)

1/01/2016 → 31/12/2018

Project: Research

Fe65 and nuclear signalling in Alzheimer's disease

Miller, C. (Primary Investigator) & Noble, W. (Co-Investigator)

1/10/2015 → 30/09/2018

Project: Research

Mechanisms of synaptic dysfunction and neurodegeneration in dementia

Hanger, D. (Primary Investigator), Gallo, J.-M. (Co-Investigator), Giese, P. (Co-Investigator), Hirth, F. (Co-Investigator), Miller, C. (Co-Investigator), Noble, W. (Co-Investigator), Pooler, A. (Co-Investigator) & Shaw, C. (Co-Investigator)

1/10/2015 → 30/09/2018

Project: Research

Correcting defective mitochondria-ER interactions as a new therapeutic target for amyotrophic lateral sclerosis (ALS)

Miller, C. (Primary Investigator) & Noble, W. (Co-Investigator)

1/09/2015 → 31/08/2017

Project: Research

Performing drug screens for modulators of endoplasmic reticulum-mitochondria associations as a new theraeutic target for dementia

Miller, C. (Primary Investigator) & Noble, W. (Co-Investigator)

1/08/2015 → 31/07/2016

Project: Research

Astrocytes influence interactions between Abeta and tau to cause synaptotoxicity in AD

Noble, W. (Primary Investigator) & Gomez Perez-Nievas, B. (Co-Investigator)

Alzheimer's Research UK

10/07/2015 → 9/07/2018

Project: Research

Correcting defective endoplasmic reticulum-mitochondria associations as a new therapeutic target for the treatment of dementia and amyotrophic lateral sclerosis

Miller, C. (Primary Investigator) & Noble, W. (Co-Investigator)

Rosetrees Trust

1/05/2015 → 31/10/2015

Project: Research

Endoplasmic reticulum-mitochondria interactions and Alzheimer's disease

Miller, C. (Primary Investigator) & Noble, W. (Co-Investigator)

Alzheimer's Research UK

1/02/2015 → 31/07/2018

Project: Research

Does P2X7 mediate Abeta- and tau- associated neurodegeneration in Alzheimer's Disease?

Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)

MedImmune Ltd

1/10/2014 → 30/09/2016

Project: Research

Astrocytes mediate the effects of soluble AB and tau to cause synaptotoxicity in AD

Noble, W. (Primary Investigator) & academic, A. (Co-Investigator)

1/10/2014 → 30/09/2017

Project: Research

Endoplasmic reticulum-mitochondria interactions and Alzheimer's disease

Miller, C. (Primary Investigator) & Noble, W. (Co-Investigator)

1/10/2014 → 30/09/2018

Project: Research

Lemur tyrosine kinase-2 and axonal transport of cdk5/p35 and protein phosphatase-1

Miller, C. (Primary Investigator) & Noble, W. (Co-Investigator)

BBSRC Biotechnology and Biological Sciences Research Council

30/09/2014 → 29/09/2017

Project: Research

Calcium abnormalities associated with neurodegeneration in Alzheimer's disease

Noble, W. (Primary Investigator)

Alzheimer's Research UK

1/09/2014 → 31/08/2015

Project: Research

Alzheimer's Research UK King's College London Network Centre

Noble, W. (Primary Investigator), Giese, P. (Co-Investigator), Hanger, D. (Co-Investigator), Hirth, F. (Co-Investigator) & Miller, C. (Co-Investigator)

Alzheimer's Research UK

1/09/2014 → 31/08/2016

Project: Research