Projects per year
- 50 - 83 out of 83 results
Search results
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Finished
Characterisation and validation of an organotypic slice culture model of Alzheimer's disease.
Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)
NC3Rs National Centre for the Replacement, Refinement and Reduction of Animals in Research
30/09/2012 → 30/09/2015
Project: Research
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Astrocyte response in Alzheimer's disease
Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)
1/07/2012 → 30/06/2015
Project: Research
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Investigating mechanisms underlying calcium dysregulation in Alzheimer's disease
Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)
4/01/2012 → 3/01/2014
Project: Research
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the Wolfson Global hub for Neurodegenerative Disorders
Shaw, C. (Primary Investigator), Ballard, C. (Co-Investigator), Gallo, J.-M. (Co-Investigator), Hanger, D. (Co-Investigator), Hodges, A. (Co-Investigator), Lovestone, S. (Co-Investigator), Miller, C. (Co-Investigator), Noble, W. (Co-Investigator) & academic, A. (Co-Investigator)
3/01/2012 → 28/02/2017
Project: Research
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Investigating the effect of Fyn tyrosine kinase on intraneuronal trafficking of tau
Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)
3/10/2011 → 2/10/2014
Project: Research
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Investigating regional astrocyte-mediated neurodegeneration in models of Alzheimer's disease
Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)
1/10/2011 → 30/09/2014
Project: Research
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ARUK Network Centre Grant
Noble, W. (Primary Investigator) & Rebollo-Mesa, I. (Co-Investigator)
1/09/2011 → 31/01/2015
Project: Research
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Astrocytes underlie differential responses to beta-amyloid induced neurotoxicity in the hippocampus and cortex: implications for Alzheimer's disease
Noble, W. (Primary Investigator)
1/07/2011 → 31/03/2013
Project: Research
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The impact of tau mutations on axonal transport and the membrane association of tau
Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)
1/04/2011 → 31/03/2014
Project: Research
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Inflammatory mediators as potential therapeutic targets for the treatment of Alzheimer's disease
Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)
1/04/2011 → 31/03/2014
Project: Research
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characterising the astrocytic inflammatory response in models of alzheimer's disease.
Noble, W. (Primary Investigator)
1/10/2010 → 30/09/2013
Project: Research
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Investigating the impact off modulating astrocyte-mediated inflammation in models of alzheimer's disease., Joint AS and BUPA application
Noble, W. (Primary Investigator), Giese, P. (Co-Investigator) & Hanger, D. (Co-Investigator)
1/10/2010 → 30/09/2013
Project: Research
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Glial -mediated inflammatory responses as pathonogenic mediators in neurodegenerative tauopathies
Noble, W. (Primary Investigator)
1/10/2010 → 30/09/2015
Project: Research
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Neuroinflammatory responses in model of Alzheimer's disease
Noble, W. (Primary Investigator) & Hanger, D. (Co-Investigator)
1/10/2010 → 31/05/2011
Project: Research
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A NOVEL MODEL OF TAUOPATHY RELEVANT TO HUMAN NEURODEGENERATIVE DISEASE
Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)
8/06/2010 → 7/06/2013
Project: Research
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The impact of tau cleavage on tangle formation and nerve cell death in dementia
Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)
1/02/2010 → 31/01/2013
Project: Research
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The impact of the Abelson family of tyrosine kinases on the development and progreesion of Alzheimer's disease
Hanger, D. (Primary Investigator) & Noble, W. (Co-Investigator)
11/01/2010 → 10/01/2013
Project: Research
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studentship
Hanger, D. (Co-Investigator) & Noble, W. (Co-Investigator)
1/10/2009 → 30/09/2012
Project: Research
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Investigating the impact of tau and fyn interactions in models of Alzheimer's disease (ART Emergency Support Application)-PhD stipend for Miss Alessia Usardi.
Noble, W. (Primary Investigator)
1/10/2009 → 31/01/2010
Project: Research
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Validation of casein kinase 1 (CK1) as a drug target to treat Alzheimer's disease and related tauopathies.
Anderton, B. (Co-Investigator), Hanger, D. (Co-Investigator) & Noble, W. (Co-Investigator)
1/06/2009 → 31/05/2012
Project: Research
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Development of a novel model of tauopathy relevant to human neurodegenerative disease
Hanger, D. (Co-Investigator) & Noble, W. (Co-Investigator)
1/02/2009 → 31/01/2013
Project: Research
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Modulation of the cannabinoid system as a potential therapeutic approach for Alzheimer`s disease
Hanger, D. (Co-Investigator) & Noble, W. (Co-Investigator)
1/10/2008 → 30/09/2011
Project: Research
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Investigating aberrant neuronal calcium regulation in Alzheimer`s disease
Noble, W. (Primary Investigator)
1/10/2008 → 30/09/2011
Project: Research
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BRC- (BRC pump priming) Investigating the presence of calpain-cleaved NCX3 as a peripheral biomarker for Alzheimer`s disease
Noble, W. (Co-Investigator)
DHSC Department of Health and Social Care
29/03/2008 → 28/02/2009
Project: Research
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A pre-clinical investigation of minocycline as a therepeutic agent for the treatment of alzheimer's disease
Hanger, D. (Co-Investigator) & Noble, W. (Co-Investigator)
2/10/2007 → 1/10/2010
Project: Research
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Investigating aberrant neuronal calcium regulation by calpain in AD
Noble, W. (Co-Investigator)
1/10/2007 → 28/10/2010
Project: Research
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Investigating neuronal calcium regulation by capain in Alzheimer's Diseases
Noble, W. (Co-Investigator)
1/10/2007 → 30/09/2012
Project: Research
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A neurodegenerative cascade in Alzheimer's disease
Noble, W. (Co-Investigator)
1/10/2006 → 1/10/2011
Project: Research
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A neurodegenerative cascade in Alzheimer's disease
Noble, W. (Co-Investigator)
1/10/2006 → 1/10/2011
Project: Research
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The role of the protein kinase, Fyn, in the mechanism of amyloid toxicity- The studentship for Ms Alessia Usardi.
Noble, W. (Co-Investigator) & Williamson, R. (Co-Investigator)
1/10/2006 → 31/01/2010
Project: Research
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The role of tau phosphorylation and the impact of protein kinase inhbitors during neurofibrillary tangle formation.
Anderton, B. (Co-Investigator), Hanger, D. (Co-Investigator) & Noble, W. (Co-Investigator)
5/10/2004 → 4/10/2007
Project: Research