Research output per year
Research output per year
Personal profile
Research interests
Professor Zhou is currently interested in the role of complement in immune regulation and trying to understand whether and how complement interacts with several pivotal cells of the immune system (e.g. antigen presenting cells, natural killer cells, mast cells and stem cells) participating in antimicrobial defence, cancer elimination, ischaemia/reperfusion injury, transplant rejection, autoimmunity and tissue remodelling. Understanding of the interaction between complement and these cells may lead to the development of new (complement-based) pharmaceutical approaches.
Research interests (short)
Roles of complement in immune regulation and its participation in immune homeostasis and pathogenesis of disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Immunology, Doctor of Philosophy, The kidney as an organ of complement synthesis
1990 → 1995
Award Date: 1 Jul 1995
Medicine, Bachelor of Medicine
Award Date: 31 Jul 1983
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Protective role for C3aR in experimental chronic pyelonephritis
Zhao, SJ., Wu, KY., Min, XY., Wang, CX., Cao, B., Ma, N., Yang, XL., Zhu, ZR., Fu, RG., Zhou, W., Yang, JR. & Li, K., 17 Oct 2022, (E-pub ahead of print) In: Faseb Journal. 36, 11, p. e22599Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli
Wu, K. Y., Cao, B., Wang, C. X., Yang, X. L., Zhao, S. J., Diao, T. Y., Lin, L. R., Zhao, G. X., Zhou, W., Yang, J. R. & Li, K., 30 Mar 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 824505.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)48 Downloads (Pure) -
Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis
Wang, N., Wu, W., Qiang, C., Ma, N., Wu, K., Liu, D., Wang, J., Yang, X., Xue, L., Diao, T., Liu, J., Li, A., Zhang, B., Li, Z., Farrar, C. A., Banda, N. K., Bayarri‐olmos, R., Garred, P., Zhou, W. & Li, K., Aug 2021, In: Arthritis and Rheumatology. 73, 8, p. 1430-1440 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)191 Downloads (Pure) -
Protective Role of C3aR (C3a Anaphylatoxin Receptor) Against Atherosclerosis in Atherosclerosis-Prone Mice
Wei, L. L., Ma, N., Wu, K. Y., Wang, J. X., Diao, T. Y., Zhao, S. J., Bai, L., Liu, E., Li, Z. F., Zhou, W., Chen, D. & Li, K., 1 Sept 2020, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 40, 9, p. 2070-2083 14 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
The C5a/C5aR2 axis promotes renal inflammation and tissue damage
Zhang, T., Wu, K-Y., Ma, N., Wei, L-L., Zhou, W. & Li, K., 19 Mar 2020, In: JCI Insight. 5, 7, e134081.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus)
Projects
- 23 Finished
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Collectin-11 as a trigger of the innate immune response in renal transplantation
Sacks, S., Rebollo-Mesa, I. & Zhou, W.
1/01/2015 → 31/12/2017
Project: Research
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Targeting C5aR in chronic inflammation, renal fibrosis and late graft dysfunction
Zhou, W., Rebollo-Mesa, I. & Sacks, S.
31/10/2014 → 30/04/2018
Project: Research
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Use of C5a-receptor humanised mice to evolve a treatment strategy in renal infections
1/10/2014 → 30/09/2017
Project: Research
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Use of C5a-receptor humanised mice to evolve a treatment strategy in renalinfections
Zhou, W., Rebollo-Mesa, I. & Sacks, S.
1/09/2014 → 31/08/2017
Project: Research
Activities
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XXI International Complement Work Shop
Wuding Zhou (Chair)
2006 → …Activity: Participating in or organising an event › Participation in conference
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at Royal Society of Medicine, London: In programme “Bench-to-bedside innate immunity in transplantation”, Talk title: Complement and ischemia reperfusion injury contributes to organ damage
Wuding Zhou (Keynote/plenary speaker)
Mar 2005 → …Activity: Participating in or organising an event › Participation in conference
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European Complement Society
Wuding Zhou (Speaker)
2005 → …Activity: Participating in or organising an event › Participation in conference
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Clinical Experimental Immunology ( 0955) (Journal)
Wuding Zhou (Editor)
2005 → …Activity: Publication peer-review and editorial work › Publication peer-review
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INTERNATIONAL IMMUNOPHARMACOLOGY (Journal)
Wuding Zhou (Editor)
2005 → …Activity: Publication peer-review and editorial work › Publication peer-review
Thesis
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Complement C3, C4 and factor B synthesis in human kidney.
Author: Zhou, W., 1995Student thesis: Doctoral Thesis › Doctor of Philosophy
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