Search results

• Active

  Accelerating the proof-of-concept study for FUS AAV gene therapy

  Lee, Y. (Primary Investigator), Lee, D. Y. (Co-Investigator) & lee, D. (Co-Investigator)

  My Name'5 Doddie Foundation

  3/02/2025 → 2/10/2025

  Project: Research

• Developing AAV Gene therapy for C9orf72 ALS/FTD

  Lee, Y. (Primary Investigator)

  My Name'5 Doddie Foundation

  1/05/2024 → 30/04/2027

  Project: Research

• Developing AAV gene therapy for Motor Neuron Disease

  Lee, Y. (Primary Investigator) & Shaw, C. (Co-Investigator)

  Motor Neurone Disease Association

  1/02/2023 → 31/01/2026

  Project: Research

• Finished

  AAV gene therapy for mutant FUS Amyotrophic Lateral Sclerosis

  Lee, Y. (Primary Investigator), Ruepp, M.-D. (Co-Investigator), Shaw, C. (Co-Investigator) & Vance, C. (Co-Investigator)

  LifeArc

  1/10/2022 → 30/09/2024

  Project: Research

• Arresting corona virus replication using microRNA to knock down the essential RDRP protein

  Shaw, C. (Primary Investigator) & Lee, Y. (Co-Investigator)

  UK Dementia Research Institute

  1/04/2020 → 31/03/2021

  Project: Research

• Viral vector gene therapy for FTD and ALS: from constructs to clinical trials

  Shaw, C. (Primary Investigator), Lee, Y. (Co-Investigator) & Farzaneh, F. (Co-Investigator)

  UK Dementia Research Institute

  1/01/2019 → 31/12/2022

  Project: Research

• Advancing gene therapy for sporadic motor neuron disease

  Shaw, C. (Primary Investigator) & Lee, Y. (Co-Investigator)

  My Name'5 Doddie Foundation

  1/08/2018 → 31/07/2021

  Project: Research

• Investigate toxicity mechanism of GGGGCC(G4C2) RNA foci and exploring the role of G4C2 RNA foci binding factor hnRNP-H in C9ORF72 ALS and FTD patients

  Shaw, C. (Primary Investigator) & Lee, Y. (Co-Investigator)

  1/01/2015 → 31/12/2016

  Project: Research

• Developing ALS gene therapy methods using CRISPR-lentivirus technology

  Lee, Y. (Primary Investigator), Nishimura, A. (Co-Investigator) & Shaw, C. (Co-Investigator)

  1/07/2014 → 1/07/2015

  Project: Research

• Modelling ALS using induced pluripotent stem cells generated by TALEN technology

  Nishimura, A. (Primary Investigator), Houart, C. (Co-Investigator), Lee, Y. (Co-Investigator) & Shaw, C. (Co-Investigator)

  ALS Association

  1/08/2013 → 31/07/2014

  Project: Research