LEAVO - A Multicentre Phase III Double-masked Randomised Controlled Non-Inferiority Trial comparing the clinical and cost effectiveness of intravitreal therapy with ranibizumab (Lucentis) vs aflibercept (Eylea) vs bevacizumab (Avastin) for Macular Oedema due to Central Retinal Vein Occlusion (CRVO)

Project: Research

Project Details

Effective start/end date1/10/201430/09/2018

Collaborative partners

  • King's College London (lead)
  • Moorfields Eye Hospital NHS Foundation Trust
  • Queen's University Belfast
  • University of Liverpool
  • University of Sheffield
  • University of Southampton


  • NIHR National Institute For Health & Care Research: £644,630.00