TY - JOUR
T1 - 3D Undersampled Golden-Radial Phase Encoding for DCE-MRA Using Inherently Regularized Iterative SENSE
AU - Prieto, Claudia
AU - Uribe, Sergio
AU - Razavi, Reza
AU - Atkinson, David
AU - Schaeffter, Tobias
PY - 2010/8
Y1 - 2010/8
N2 - One of the current limitations of dynamic contrast-enhanced MR angiography is the requirement of both high spatial and high temporal resolution. Several undersampling techniques have been proposed to overcome this problem. However, in most of these methods the tradeoff between spatial and temporal resolution is constant for all the time frames and needs to be specified prior to data collection. This is not optimal for dynamic contrast-enhanced MR angiography where the dynamics of the process are difficult to predict and the image quality requirements are changing during the bolus passage. Here, we propose a new highly undersampled approach that allows the retrospective adaptation of the spatial and temporal resolution. The method combines a three-dimensional radial phase encoding trajectory with the golden angle profile order and non-Cartesian Sensitivity Encoding (SENSE) reconstruction. Different regularization images, obtained from the same acquired data, are used to stabilize the non-Cartesian SENSE reconstruction for the different phases of the bolus passage. The feasibility of the proposed method was demonstrated on a numerical phantom and in three-dimensional intracranial dynamic contrast-enhanced MR angiography of healthy volunteers. The acquired data were reconstructed retrospectively with temporal resolutions from 1.2 sec to 8.1 sec, providing a good depiction of small vessels, as well as distinction of different temporal phases. Magn Reson Med 64:514-526, 2010. (C) 2010 Wiley-Liss, Inc.
AB - One of the current limitations of dynamic contrast-enhanced MR angiography is the requirement of both high spatial and high temporal resolution. Several undersampling techniques have been proposed to overcome this problem. However, in most of these methods the tradeoff between spatial and temporal resolution is constant for all the time frames and needs to be specified prior to data collection. This is not optimal for dynamic contrast-enhanced MR angiography where the dynamics of the process are difficult to predict and the image quality requirements are changing during the bolus passage. Here, we propose a new highly undersampled approach that allows the retrospective adaptation of the spatial and temporal resolution. The method combines a three-dimensional radial phase encoding trajectory with the golden angle profile order and non-Cartesian Sensitivity Encoding (SENSE) reconstruction. Different regularization images, obtained from the same acquired data, are used to stabilize the non-Cartesian SENSE reconstruction for the different phases of the bolus passage. The feasibility of the proposed method was demonstrated on a numerical phantom and in three-dimensional intracranial dynamic contrast-enhanced MR angiography of healthy volunteers. The acquired data were reconstructed retrospectively with temporal resolutions from 1.2 sec to 8.1 sec, providing a good depiction of small vessels, as well as distinction of different temporal phases. Magn Reson Med 64:514-526, 2010. (C) 2010 Wiley-Liss, Inc.
U2 - 10.1002/mrm.22446
DO - 10.1002/mrm.22446
M3 - Article
SN - 1522-2594
VL - 64
SP - 514
EP - 526
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 2
ER -