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A clinical opinion on how to manage the risk of preterm birth in twins based on literature review

Research output: Contribution to journalReview articlepeer-review

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A clinical opinion on how to manage the risk of preterm birth in twins based on literature review. / Collins, Anna; Shennan, Andrew.

In: The Journal of Maternal-Fetal & Neonatal Medicine, Vol. 29, No. 7, 02.04.2016, p. 1125-1130.

Research output: Contribution to journalReview articlepeer-review

Harvard

Collins, A & Shennan, A 2016, 'A clinical opinion on how to manage the risk of preterm birth in twins based on literature review', The Journal of Maternal-Fetal & Neonatal Medicine, vol. 29, no. 7, pp. 1125-1130. https://doi.org/10.3109/14767058.2015.1037734

APA

Collins, A., & Shennan, A. (2016). A clinical opinion on how to manage the risk of preterm birth in twins based on literature review. The Journal of Maternal-Fetal & Neonatal Medicine, 29(7), 1125-1130. https://doi.org/10.3109/14767058.2015.1037734

Vancouver

Collins A, Shennan A. A clinical opinion on how to manage the risk of preterm birth in twins based on literature review. The Journal of Maternal-Fetal & Neonatal Medicine. 2016 Apr 2;29(7):1125-1130. https://doi.org/10.3109/14767058.2015.1037734

Author

Collins, Anna ; Shennan, Andrew. / A clinical opinion on how to manage the risk of preterm birth in twins based on literature review. In: The Journal of Maternal-Fetal & Neonatal Medicine. 2016 ; Vol. 29, No. 7. pp. 1125-1130.

Bibtex Download

@article{a4d05289bc554b76ad5de242691f4ff5,
title = "A clinical opinion on how to manage the risk of preterm birth in twins based on literature review",
abstract = "Twin pregnancies are prone to preterm birth and consequent morbidity. There is an increasing evidence base concerning the prediction and prevention of preterm birth in singletons, including the reduction of morbidity with therapies such as magnesium sulphate and antenatal corticosteroids. However, the research in twins is less clear, partly due to fewer numbers being investigated, but also evidence is largely based on twins without a previous history. Prophylactic interventions such as cerclage, progesterone and vaginal pessaries are increasingly showing benefit in singleton pregnancies with a prior history and when the cervix is short. Cerclage in twins has not been adequately researched in women with previous preterm birth, and as with singletons should not be used on the basis of a short cervix alone. Vaginal progesterone does not work in twins, but its value in high-risk twins, with a prior history and short cervix is uncertain. The vaginal pessary may be valuable in the twin with a short cervix. Currently, it is reasonable to extrapolate some of the evidence from singletons to twins, e.g. with antenatal corticosteroids and magnesium sulphate. Cerclage, vaginal pessaries and progesterone should not be routinely used in twin pregnancies without an additional high-risk factor such as prior history of preterm birth or short cervix, until further evidence is obtained.",
keywords = "Cerclage, preterm birth, twins",
author = "Anna Collins and Andrew Shennan",
year = "2016",
month = apr,
day = "2",
doi = "10.3109/14767058.2015.1037734",
language = "English",
volume = "29",
pages = "1125--1130",
journal = " The Journal of Maternal-Fetal & Neonatal Medicine",
issn = "1476-7058",
publisher = "Taylor and Francis",
number = "7",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - A clinical opinion on how to manage the risk of preterm birth in twins based on literature review

AU - Collins, Anna

AU - Shennan, Andrew

PY - 2016/4/2

Y1 - 2016/4/2

N2 - Twin pregnancies are prone to preterm birth and consequent morbidity. There is an increasing evidence base concerning the prediction and prevention of preterm birth in singletons, including the reduction of morbidity with therapies such as magnesium sulphate and antenatal corticosteroids. However, the research in twins is less clear, partly due to fewer numbers being investigated, but also evidence is largely based on twins without a previous history. Prophylactic interventions such as cerclage, progesterone and vaginal pessaries are increasingly showing benefit in singleton pregnancies with a prior history and when the cervix is short. Cerclage in twins has not been adequately researched in women with previous preterm birth, and as with singletons should not be used on the basis of a short cervix alone. Vaginal progesterone does not work in twins, but its value in high-risk twins, with a prior history and short cervix is uncertain. The vaginal pessary may be valuable in the twin with a short cervix. Currently, it is reasonable to extrapolate some of the evidence from singletons to twins, e.g. with antenatal corticosteroids and magnesium sulphate. Cerclage, vaginal pessaries and progesterone should not be routinely used in twin pregnancies without an additional high-risk factor such as prior history of preterm birth or short cervix, until further evidence is obtained.

AB - Twin pregnancies are prone to preterm birth and consequent morbidity. There is an increasing evidence base concerning the prediction and prevention of preterm birth in singletons, including the reduction of morbidity with therapies such as magnesium sulphate and antenatal corticosteroids. However, the research in twins is less clear, partly due to fewer numbers being investigated, but also evidence is largely based on twins without a previous history. Prophylactic interventions such as cerclage, progesterone and vaginal pessaries are increasingly showing benefit in singleton pregnancies with a prior history and when the cervix is short. Cerclage in twins has not been adequately researched in women with previous preterm birth, and as with singletons should not be used on the basis of a short cervix alone. Vaginal progesterone does not work in twins, but its value in high-risk twins, with a prior history and short cervix is uncertain. The vaginal pessary may be valuable in the twin with a short cervix. Currently, it is reasonable to extrapolate some of the evidence from singletons to twins, e.g. with antenatal corticosteroids and magnesium sulphate. Cerclage, vaginal pessaries and progesterone should not be routinely used in twin pregnancies without an additional high-risk factor such as prior history of preterm birth or short cervix, until further evidence is obtained.

KW - Cerclage

KW - preterm birth

KW - twins

UR - http://www.scopus.com/inward/record.url?scp=84955312323&partnerID=8YFLogxK

U2 - 10.3109/14767058.2015.1037734

DO - 10.3109/14767058.2015.1037734

M3 - Review article

C2 - 26000625

AN - SCOPUS:84955312323

VL - 29

SP - 1125

EP - 1130

JO - The Journal of Maternal-Fetal & Neonatal Medicine

JF - The Journal of Maternal-Fetal & Neonatal Medicine

SN - 1476-7058

IS - 7

ER -

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