Abstract
19 A comparison of protection given from toothpastes to erosion
Wednesday, September 12, 2012: 2 p.m. - 4 p.m.
Location: Veranda 1 (Finlandia Hall)
Presentation Type: Oral Session
R. AUSTIN1, L. MARTENS2, S. EVERSOLE3, and D. BARTLETT1, 1Dental Institute, King's College London, London, United Kingdom, 2Paediatric Dentistry and Special Care, University of Ghent-Belgium, Ghent, Belgium, 3Oral Care, Procter & Gamble Company, Mason, OH
Objectives: The aim of this in vitro study was to assess the potential of toothpastes to protect human tooth enamel against erosive dietary acids.
Methods: Polished human enamel specimens (n=4/gp) were immersed in 20ml of human saliva for 60mins to formulate initial pellicle formation. Each group was subjected to erosion-cycling regimen consisting of 4 cycles/day over 5 days. Each cycle consisted of immersion in a toothpaste slurry for 2mins (1:3 toothpaste/fresh pooled human saliva), 60mins remineralisation in human saliva and 10mins in 1% citric acid at natural pH. Four enamel specimens were tested each with Crest Cavity (1100ppm F as NaF), Aquafresh White & Complete Care (1450ppm F as NaF) Sensodyne Pronamel (1450ppm F as NaF), Signal Integral 8 (1450 ppm F as NaF), Colgate Total (1450ppm F as NaF), GC Toothmouse (0ppm F), Rembrandt Complete (1450ppm F as NaF), Meridol (1400ppm F as 350ppm AmF+1050ppm SnF2), Crest ProHealth (1100ppm as SnF2) and Oral B ProExpert (1450ppm F as 350ppm NaF+1100ppm SnF2). Specimens were analysed using transverse microradiography (TMR) and profilometry and mean surface loss calculated using previously validated methods.
Results: The mean step height for all pastes was 17.9um with the lowest being Oral B ProExpert but there were no statistically significant differences between the products. Data from microradiography using Fisher’s Least Significant Difference (LSD) test showed that the least protective toothpastes were: Crest Cavity, Aquafresh, Sensodyne Pronamel, Signal 8 and Colgate Total. There were no significant differences within this group. A signficantly increased protective effect (p < 0.05) compared to all other pastes was found for Crest ProHealth and Oral B ProExpert.
Conclusions: Within the limitations of this study toothpastes with stabilised stannous technology appeared to offer significantly better protection of human enamel. Although not significantly different, the data from the profilometry showed a similar trend to the TMR.
This abstract is based on research that was funded entirely or partially by an outside source: Proctor and Gamble
Keywords: Dentifrices, Enamel, Erosion and Fluoride
Wednesday, September 12, 2012: 2 p.m. - 4 p.m.
Location: Veranda 1 (Finlandia Hall)
Presentation Type: Oral Session
R. AUSTIN1, L. MARTENS2, S. EVERSOLE3, and D. BARTLETT1, 1Dental Institute, King's College London, London, United Kingdom, 2Paediatric Dentistry and Special Care, University of Ghent-Belgium, Ghent, Belgium, 3Oral Care, Procter & Gamble Company, Mason, OH
Objectives: The aim of this in vitro study was to assess the potential of toothpastes to protect human tooth enamel against erosive dietary acids.
Methods: Polished human enamel specimens (n=4/gp) were immersed in 20ml of human saliva for 60mins to formulate initial pellicle formation. Each group was subjected to erosion-cycling regimen consisting of 4 cycles/day over 5 days. Each cycle consisted of immersion in a toothpaste slurry for 2mins (1:3 toothpaste/fresh pooled human saliva), 60mins remineralisation in human saliva and 10mins in 1% citric acid at natural pH. Four enamel specimens were tested each with Crest Cavity (1100ppm F as NaF), Aquafresh White & Complete Care (1450ppm F as NaF) Sensodyne Pronamel (1450ppm F as NaF), Signal Integral 8 (1450 ppm F as NaF), Colgate Total (1450ppm F as NaF), GC Toothmouse (0ppm F), Rembrandt Complete (1450ppm F as NaF), Meridol (1400ppm F as 350ppm AmF+1050ppm SnF2), Crest ProHealth (1100ppm as SnF2) and Oral B ProExpert (1450ppm F as 350ppm NaF+1100ppm SnF2). Specimens were analysed using transverse microradiography (TMR) and profilometry and mean surface loss calculated using previously validated methods.
Results: The mean step height for all pastes was 17.9um with the lowest being Oral B ProExpert but there were no statistically significant differences between the products. Data from microradiography using Fisher’s Least Significant Difference (LSD) test showed that the least protective toothpastes were: Crest Cavity, Aquafresh, Sensodyne Pronamel, Signal 8 and Colgate Total. There were no significant differences within this group. A signficantly increased protective effect (p < 0.05) compared to all other pastes was found for Crest ProHealth and Oral B ProExpert.
Conclusions: Within the limitations of this study toothpastes with stabilised stannous technology appeared to offer significantly better protection of human enamel. Although not significantly different, the data from the profilometry showed a similar trend to the TMR.
This abstract is based on research that was funded entirely or partially by an outside source: Proctor and Gamble
Keywords: Dentifrices, Enamel, Erosion and Fluoride
| Original language | English |
|---|---|
| Journal | Journal of Dental Research |
| Volume | 91 |
| Issue number | Spec Iss C |
| Publication status | Published - 2012 |