Abstract
This study compares the withdrawal responses of methadone and heroin addicts during a ten-day in-patient detoxification programme with methadone. Contrary to suggestions in the literature, the methadone group reported more severe withdrawal symptoms during both the acute withdrawal phase and the recovery phase. There were no differences between the two groups in onset or duration of symptoms. Whereas there may be reasons to favour methadone as a maintenance drug, its use may lead to difficulties during withdrawal.
| Original language | English |
|---|---|
| Article number | N/A |
| Pages (from-to) | 697-699 |
| Number of pages | 3 |
| Journal | British Journal of Psychiatry |
| Volume | 158 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 1991 |
Keywords
- Adult
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Female
- Heroin
- Heroin Dependence
- Humans
- Male
- Methadone
- Neurologic Examination
- Opioid-Related Disorders
- Substance Withdrawal Syndrome
