A Deep-Discrete Learning Framework for Spherical Surface Registration

Mohamed A. Suliman*, Logan Z.J. Williams, Abdulah Fawaz, Emma C. Robinson

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

9 Citations (Scopus)
146 Downloads (Pure)

Abstract

Cortical surface registration is a fundamental tool for neuroimaging analysis that has been shown to improve the alignment of functional regions relative to volumetric approaches. Classically, image registration is performed by optimizing a complex objective similarity function, leading to long run times. This contributes to a convention for aligning all data to a global average reference frame that poorly reflects the underlying cortical heterogeneity. In this paper, we propose a novel unsupervised learning-based framework that converts registration to a multi-label classification problem, where each point in a low-resolution control grid deforms to one of fixed, finite number of endpoints. This is learned using a spherical geometric deep learning architecture, in an end-to-end unsupervised way, with regularization imposed using a deep Conditional Random Field (CRF). Experiments show that our proposed framework performs competitively, in terms of similarity and areal distortion, relative to the most popular classical surface registration algorithms and generates smoother deformations than other learning-based surface registration methods, even in subjects with atypical cortical morphology. The code can be found in https://github.com/mohamedasuliman/DDR/.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2022 - 25th International Conference, Proceedings
EditorsLinwei Wang, Qi Dou, P. Thomas Fletcher, Stefanie Speidel, Shuo Li
PublisherSpringer Science and Business Media Deutschland GmbH
Pages119-129
Number of pages11
ISBN (Print)9783031164453
DOIs
Publication statusPublished - 17 Sept 2022
Event25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022 - Singapore, Singapore
Duration: 18 Sept 202222 Sept 2022

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume13436 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022
Country/TerritorySingapore
CitySingapore
Period18/09/202222/09/2022

Keywords

  • Conditional random fields
  • Cortical surface registration
  • Deep learning
  • Unsupervised learning

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