A Gender comparison of Cardiovascular Responses to Lower Body Negative Pressure Exposure

TY - JOUR

T1 - A Gender comparison of Cardiovascular Responses to Lower Body Negative Pressure Exposure

AU - Russomano, Thais

AU - May, Francisca

AU - Dalmarco, Gustavo

AU - BAPTISTA, Rafael R

AU - Gauger, Peter

AU - Petrat, Guido

AU - Beck, Luis

PY - 2015

Y1 - 2015

N2 - The purpose of this study was to compare the LBNP tolerance between genders. Twenty healthy subjects (8 men, 12 women) were exposed to 10 min of 45mmHg LBNP. Baseline was taken in the sitting and supine positions. Finger blood pressure and heart rate (HR) were recorded continuously. Stroke volume (SV), cardiac output (CO) and total peripheral resistance (TPR) were calculated by a pulse contour method. Baseline cardiovascular variables were similar in all females, independently of the menstrual cycle phase and they were considered as one group. Seven of 8 men and 7 of 12 women completed the 10 min of LBNP. Non-finishers (n=6) increased heart rate, decreased systolic blood pressure, mean blood pressure, calculated SV and CO in comparison with the Finisher (n=14) group (p<0.05). Both groups, however, maintained TPR unchanged during the exposure to LBNP. This suggests the tolerance to LBNP is related to the capability of both avoiding too large a decrease in SV, and inducing an adequate vasoconstriction response

AB - The purpose of this study was to compare the LBNP tolerance between genders. Twenty healthy subjects (8 men, 12 women) were exposed to 10 min of 45mmHg LBNP. Baseline was taken in the sitting and supine positions. Finger blood pressure and heart rate (HR) were recorded continuously. Stroke volume (SV), cardiac output (CO) and total peripheral resistance (TPR) were calculated by a pulse contour method. Baseline cardiovascular variables were similar in all females, independently of the menstrual cycle phase and they were considered as one group. Seven of 8 men and 7 of 12 women completed the 10 min of LBNP. Non-finishers (n=6) increased heart rate, decreased systolic blood pressure, mean blood pressure, calculated SV and CO in comparison with the Finisher (n=14) group (p<0.05). Both groups, however, maintained TPR unchanged during the exposure to LBNP. This suggests the tolerance to LBNP is related to the capability of both avoiding too large a decrease in SV, and inducing an adequate vasoconstriction response

KW - Gender difference

KW - Menstrual Cycle

KW - cardiovascular response

KW - LBNP tolerance

M3 - Article

SN - 2328-4080

VL - 3

SP - 95

EP - 101

JO - American Journal of Medical and Biological Research

JF - American Journal of Medical and Biological Research

IS - 4

ER -