A model of memory impairment in schizophrenia: Cognitive and clinical factors associated with memory efficiency and memory errors

Gildas Brebion*, Rodrigo A. Bressan, Ruth I. Ohlsen, Anthony S. David

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Background: Memory impairments in patients with schizophrenia have been associated with various cognitive and clinical factors. Hallucinations have been more specifically associated with errors stemming from source monitoring failure.

Methods: We conducted a broad investigation of verbal memory and visual memory as well as source memory functioning in a sample of patients with schizophrenia. Various memory measures were tallied, and we studied their associations with processing speed, working memory span, and positive, negative, and depressive symptoms.

Results: Superficial and deep memory processes were differentially associated with processing speed, working memory span, avolition, depression, and attention disorders. Auditory verbal and visual hallucinations were differentially associated with specific types of source memory error.

Conclusions: We integrated all the results into a revised version of a previously published model of memory functioning in schizophrenia. The model describes the factors that affect memory efficiency, as well as the cognitive underpinnings of hallucinations within the source monitoring framework.

Original languageEnglish
Pages (from-to)70-77
Number of pages8
JournalSchizophrenia Research
Volume151
Issue number1-3
DOIs
Publication statusPublished - Dec 2013

Keywords

  • Memory
  • Source monitoring
  • Schizophrenia
  • Processing speed
  • Hallucinations
  • AUDITORY VERBAL HALLUCINATIONS
  • PROCESSING SPEED
  • INTRINSIC MOTIVATION
  • DYSFUNCTION
  • SYMPTOMS
  • DEFICITS
  • PERFORMANCE
  • MECHANISMS
  • DEPRESSION
  • PSYCHOSIS

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