A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Michelle Ma; John A. Karas; Jonathan M. White; Denis Scanlon; Paul S. Donnelly

doi:10.1039/b903426a

A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Michelle Ma, John A. Karas, Jonathan M. White, Denis Scanlon, Paul S. Donnelly

Imaging Chemistry & Biology

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

Abstract

A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]-octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64.

Original language	English
Article number	N/A
Pages (from-to)	3237-3239
Number of pages	3
Journal	Chemical communications (Cambridge, England)
Volume	N/A
Issue number	22
DOIs	https://doi.org/10.1039/b903426a
Publication status	Published - 14 Jun 2009

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10.1039/b903426a

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title = "A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides",

abstract = "A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]-octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64.",

author = "Michelle Ma and Karas, {John A.} and White, {Jonathan M.} and Denis Scanlon and Donnelly, {Paul S.}",

year = "2009",

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language = "English",

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journal = "Chemical communications (Cambridge, England)",

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publisher = "Royal Society of Chemistry",

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A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides. / Ma, Michelle; Karas, John A.; White, Jonathan M. et al.
In: Chemical communications (Cambridge, England), Vol. N/A, No. 22, N/A, 14.06.2009, p. 3237-3239.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

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T2 - a cage amine ligand with a carboxylate functional group for conjugation to peptides

AU - Ma, Michelle

AU - Karas, John A.

AU - White, Jonathan M.

AU - Scanlon, Denis

AU - Donnelly, Paul S.

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AB - A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]-octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64.

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DO - 10.1039/b903426a

M3 - Article

SN - 1364-548X

VL - N/A

SP - 3237

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JF - Chemical communications (Cambridge, England)

IS - 22

M1 - N/A

ER -

A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Abstract

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