A practical guide to the use of thiopurines in oral medicine

E. A. Hullah*, P. A. Blaker, A. M. Marinaki, M. P. Escudier, J. D. Sanderson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Thiopurines are widely used as first-line immunosuppressive therapies in the management of chronic inflammatory oral disease. However, despite over half a century of clinical experience, the evidence base for their use is limited. The aims of this paper were to review the evidence for the use of thiopurines in oral medicine and provide a contemporary model of thiopurine metabolism and mechanism of action and a rationale for clinical use and safe practice.

Original languageEnglish
Pages (from-to)761-768
Number of pages8
JournalJournal of Oral Pathology and Medicine
Volume44
Issue number10
Early online date19 Dec 2014
DOIs
Publication statusPublished - 1 Nov 2015

Keywords

  • Azathioprine
  • Oral diseases
  • Oral medicine
  • Thiopurines

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