A pragmatic lifestyle modification programme reduces the incidence of predictors of cardio-metabolic disease and dysglycaemia in a young healthy urban South Asian population: a randomised controlled trial

Mahen Wijesuriya; Nikolaos Fountoulakis; Nicola Guess; Sarath Banneheka; Laksha Vasantharajah; Martin Gulliford; Giancarlo Viberti; Luigi Gnudi; Janaka Karalliedde

doi:10.1186/s12916-017-0905-6

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A pragmatic lifestyle modification programme reduces the incidence of predictors of cardio-metabolic disease and dysglycaemia in a young healthy urban South Asian population: a randomised controlled trial

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Mahen Wijesuriya, Nikolaos Fountoulakis, Nicola Guess, Sarath Banneheka, Laksha Vasantharajah, Martin Gulliford, Giancarlo Viberti, Luigi Gnudi, Janaka Karalliedde

Original language	English
Article number	146
Journal	BMC Medicine
Volume	15
Issue number	1
Early online date	30 Aug 2017
DOIs	https://doi.org/10.1186/s12916-017-0905-6
Accepted/In press	29 Jun 2017
E-pub ahead of print	30 Aug 2017
Published	30 Aug 2017
Additional links	http://www.scopus.com/inward/record.url?scp=85028459041&partnerID=8YFLogxK

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Abstract

There is an increasing incidence of type 2 diabetes mellitus (T2DM) in young urban South-Asians. We tested the effect of a pragmatic trimonthly lifestyle modification (LSM) programme (P-LSM) versus a less-intensive 12-monthly control LSM (C-LSM) intervention on a primary composite endpoint of predictors of cardio-metabolic disease (new onset T2DM, hypertension, impaired glucose tolerance (IGT), impaired fasting glycaemia (IFG) and markers of cardio-renal disease) in participants aged 5--40 years with risk factors for T2DM.

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A pragmatic lifestyle modification programme reduces the incidence of predictors of cardio-metabolic disease and dysglycaemia in a young healthy urban South Asian population: a randomised controlled trial

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