TY - JOUR
T1 - A pre-post pilot study of electronic cigarettes to reduce smoking in people with severe mental illness
AU - Hickling, Lauren M.
AU - Perez-Iglesias, Rocio
AU - McNeill, Ann Denise
AU - Dawkins, Lynne
AU - Moxham, John
AU - Ruffell, Tamatha Ophelia
AU - Sendt, Kyra-Verena
AU - McGuire, Philip
PY - 2018/7/10
Y1 - 2018/7/10
N2 - BackgroundSmoking is the largest single contributor to poor physical health and increased mortality in people with serious mental illnesses. The aim of the study was to investigate the utility of electronic cigarettes (e-cigarettes) as a harm reduction intervention in this population.MethodFifty tobacco smokers with a psychotic disorder were enrolled onto a 24-week pilot study (ClinicalTrials.gov: NCT02212041) investigating the efficacy of a 6-week free e-cigarette intervention to reduce smoking. Cigarette and e-cigarette use was self-reported at weekly visits, and verified using carbon monoxide tests. Psychopathology, e-cigarette acceptability and adverse effects were assessed using standardised scales.ResultsThere was a significant (⩾50%) reduction in cigarettes consumed per day between baseline and week 6 [F(2.596,116.800) = 25.878, p < 0.001], and e-cigarette use was stable during this period [F(2.932,46.504) = 2.023, p = 0.115]. These changes were verified by significant carbon monoxide reductions between these time points [F(3.335,126.633) = 5.063, p = 0.002].ConclusionsThe provision of e-cigarettes is a potentially useful harm reduction intervention in smokers with a psychotic disorder.
AB - BackgroundSmoking is the largest single contributor to poor physical health and increased mortality in people with serious mental illnesses. The aim of the study was to investigate the utility of electronic cigarettes (e-cigarettes) as a harm reduction intervention in this population.MethodFifty tobacco smokers with a psychotic disorder were enrolled onto a 24-week pilot study (ClinicalTrials.gov: NCT02212041) investigating the efficacy of a 6-week free e-cigarette intervention to reduce smoking. Cigarette and e-cigarette use was self-reported at weekly visits, and verified using carbon monoxide tests. Psychopathology, e-cigarette acceptability and adverse effects were assessed using standardised scales.ResultsThere was a significant (⩾50%) reduction in cigarettes consumed per day between baseline and week 6 [F(2.596,116.800) = 25.878, p < 0.001], and e-cigarette use was stable during this period [F(2.932,46.504) = 2.023, p = 0.115]. These changes were verified by significant carbon monoxide reductions between these time points [F(3.335,126.633) = 5.063, p = 0.002].ConclusionsThe provision of e-cigarettes is a potentially useful harm reduction intervention in smokers with a psychotic disorder.
KW - SMOKING
KW - MENTAL HEALTH
KW - Electronic cigarettes
KW - HARM REDUCTION
U2 - 10.1017/S0033291718001782
DO - 10.1017/S0033291718001782
M3 - Article
SN - 0033-2917
JO - Psychological Medicine
JF - Psychological Medicine
ER -