A single rapid point-of-care placental growth factor determination as an aid in the diagnosis of preeclampsia

Ulla B. Knudsen, Camilla S. Kronborg, Peter von Dadelszen, Ken Kupfer, Seok-Won Lee, Erik Vittinghus, Jim G. Allen, Christopher W. Redman

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)

Abstract

Objectives To evaluate the clinical performance of a rapid point-of-care test, Triage PLGF (Alere, San Diego) in the diagnosis of preeclampsia. Study design For the reference range 2212 plasma samples were collected from 595 subjects with normotensive pregnancies, between week 17 of gestation and delivery. In the case-control part, two cohorts of women with preeclampsia (80 women) were matched for maternal age, gestational age (GA) at sampling and parity with normotensive women who delivered at 37weeks or more. Results The areas under the receiver operating characteristic curves (GA
Original languageEnglish
Pages (from-to)8-15
Number of pages8
JournalPregnancy Hypertension: An International Journal of Women's Cardiovascular Health
Volume2
Issue number1
Early online date8 Sept 2011
DOIs
Publication statusPublished - Jan 2012

Keywords

  • Angiogenesis
  • Biomarkers
  • PlGF
  • Preeclampsia
  • Preterm preeclampsia
  • Triage PLGF test

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