A statistical and biological response to an informatics appraisal of healthy aging gene signatures

James A. Timmons*, Iain J. Gallagher, Sanjana Sood, Bethan Phillips, Hannah Crossland, Robert Howard, William E. Kraus, Philip J. Atherton

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Jacob and Speed did not identify even a single example of a '150-gene-set' that was statistically significant at classifying Alzheimer's disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below.

Original languageEnglish
Article number152
JournalGenome Biology
Volume20
Issue number1
DOIs
Publication statusPublished - 2 Aug 2019

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