@article{300d6a187d7544008dbb5fdb9f890a34,
title = "A Systematic Analysis of Metal and Metalloid Concentrations in Eight Zebrafish Recirculating Water Systems",
abstract = "Metals and metalloids are integral to biological processes and play key roles in physiology and metabolism. Nonetheless, overexposure to some metals or lack of others can lead to serious health consequences. In this study, eight zebrafish facilities collaborated to generate a multielement analysis of their centralized recirculating water systems. We report a first set of average concentrations for 46 elements detected in zebrafish facilities. Our results help to establish an initial baseline for trouble-shooting purposes, and in general for safe ranges of metal concentrations in recirculating water systems, supporting reproducible scientific research outcomes with zebrafish.",
keywords = "animal welfare, aquatic models, environment, fish nutrition, metal requirement, metal toxicity, reproducibility, standards, water quality, zebrafish husbandry",
author = "Xavier Langa and Patrick Neuhaus and David Lains and Stewart, {Theodora J.} and Nadine Borel and Certal, {Ana C.} and Monteiro, {Joana F.} and Peter Alestr{\"o}m and Eduardo Diaz and Indre Piragyte and Lars Br{\"a}utigam and Rodolfo V{\'a}zquez and Ruslan Hlushchuk and Lorenz Gfeller and Adrien Mestrot and Moritz Bigalke and Varga, {Zoltan M.} and Nadia Mercader",
note = "Funding Information: This work was partially funded by the European Research Council ERC Consolidator grant 819717, Congento Lisboa-01-0145-FEDER-022170, cofinanced by FCT (Portugal) and Lisboa2020, under the Portugal2020 agreement (European Regional Development Fund). D.L. and Z.M.V. of the ZIRC gratefully acknowledge support by the NIH/ORIP (P40 OD011021). Publisher Copyright: {\textcopyright} Xavier Langa et al., 2021; Published by Mary Ann Liebert, Inc. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = aug,
doi = "10.1089/zeb.2020.1970",
language = "English",
volume = "18",
pages = "252--264",
journal = "Zebrafish",
issn = "1545-8547",
publisher = "Mary Ann Liebert Inc.",
number = "4",
}
