A systematic review of factors affecting intended and actual adherence with antiviral medication as treatment or prophylaxis in seasonal and pandemic flu

TY - JOUR

T1 - A systematic review of factors affecting intended and actual adherence with antiviral medication as treatment or prophylaxis in seasonal and pandemic flu

AU - Smith, Louise

AU - D'Antoni, Donatella

AU - Jain, Vageesh

AU - Pearce, Julia M

AU - Weinman, John Alfred

AU - Rubin, Gideon James

PY - 2016/11

Y1 - 2016/11

N2 - Aim: The aim of this study was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza.Method: Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence to antivirals. Results: Twenty-six studies were included in the review; twenty identified through the literature search and six through other means. Of these studies, eighteen assessed predictors of actual adherence to antivirals whereas eight assessed predictors of intended adherence. The most commonly found predictor of and self-reported reason for non-adherence was the occurrence of side-effects. Other predictors include perceptions surrounding self-efficacy, response-efficacy and perceived personal consequences as well as social influences of others’ experiences of taking antivirals.Conclusion: Predictors identified in this review can be used to help inform communications in order to increase adherence to antivirals in both seasonal and pandemic influenza.

AB - Aim: The aim of this study was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza.Method: Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence to antivirals. Results: Twenty-six studies were included in the review; twenty identified through the literature search and six through other means. Of these studies, eighteen assessed predictors of actual adherence to antivirals whereas eight assessed predictors of intended adherence. The most commonly found predictor of and self-reported reason for non-adherence was the occurrence of side-effects. Other predictors include perceptions surrounding self-efficacy, response-efficacy and perceived personal consequences as well as social influences of others’ experiences of taking antivirals.Conclusion: Predictors identified in this review can be used to help inform communications in order to increase adherence to antivirals in both seasonal and pandemic influenza.

KW - Adherence

KW - Antiviral

KW - Influenza

KW - Pandemic

U2 - 10.1111/irv.12406

DO - 10.1111/irv.12406

M3 - Article

SN - 1750-2640

VL - 10

SP - 462

EP - 478

JO - Influenza And Other Respiratory Viruses

JF - Influenza And Other Respiratory Viruses

IS - 6

ER -