A systematic review of multisensory cognitive-affective integration in schizophrenia

Huai Hsuan Tseng; Matthijs G. Bossong; Gemma Modinos; Kuan Ming Chen; Philip McGuire; Paul Allen

doi:10.1016/j.neubiorev.2015.04.019

A systematic review of multisensory cognitive-affective integration in schizophrenia

Huai Hsuan Tseng^*, Matthijs G. Bossong, Gemma Modinos, Kuan Ming Chen, Philip McGuire, Paul Allen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

The etymology of schizophrenia implies poor functional integration of sensory, cognitive and affective processes. Multisensory integration (MSI) is a spontaneous perceptual-cognitive process by which relevant information from multiple sensory modalities is extracted to generate a holistic experience. Deficits in MSI may hinder prompt and appropriate behavioural responses in a complex and transient environment. Despite extensive investigation of sensory, cognitive and affective processing in patients with schizophrenia, little is known about how MSI is affected in the illness. We systemically searched the PubMed electronic database and reviewed twenty-nine behavioural and neuroimaging studies examining MSI in patients with schizophrenia. The available evidence indicates impaired MSI for non-emotional stimuli in schizophrenia, especially for linguistic information. There is also evidence for altered MSI for emotional stimuli, although findings are inconsistent and may be modality-specific. Brain functional alterations in the superior temporal cortex and inferior frontal cortex appear to underlie the deficits in both non-emotional and emotional MSI. The limitations of the experimental paradigms used and directions for future research are also discussed.

Original language	English
Pages (from-to)	444-452
Number of pages	9
Journal	Neuroscience and Biobehavioral Reviews
Volume	55
DOIs	https://doi.org/10.1016/j.neubiorev.2015.04.019
Publication status	Published - 1 Aug 2015

Keywords

Congruent facilitation
Emotion
Functional magnetic resonance imaging
Incongruent interference
Multi-sensory integration
Schizophrenia

Access to Document

10.1016/j.neubiorev.2015.04.019

Cite this

@article{37af9a0af9fb43b2a6c0ee53199e52cf,

title = "A systematic review of multisensory cognitive-affective integration in schizophrenia",

abstract = "The etymology of schizophrenia implies poor functional integration of sensory, cognitive and affective processes. Multisensory integration (MSI) is a spontaneous perceptual-cognitive process by which relevant information from multiple sensory modalities is extracted to generate a holistic experience. Deficits in MSI may hinder prompt and appropriate behavioural responses in a complex and transient environment. Despite extensive investigation of sensory, cognitive and affective processing in patients with schizophrenia, little is known about how MSI is affected in the illness. We systemically searched the PubMed electronic database and reviewed twenty-nine behavioural and neuroimaging studies examining MSI in patients with schizophrenia. The available evidence indicates impaired MSI for non-emotional stimuli in schizophrenia, especially for linguistic information. There is also evidence for altered MSI for emotional stimuli, although findings are inconsistent and may be modality-specific. Brain functional alterations in the superior temporal cortex and inferior frontal cortex appear to underlie the deficits in both non-emotional and emotional MSI. The limitations of the experimental paradigms used and directions for future research are also discussed.",

keywords = "Congruent facilitation, Emotion, Functional magnetic resonance imaging, Incongruent interference, Multi-sensory integration, Schizophrenia",

author = "Tseng, {Huai Hsuan} and Bossong, {Matthijs G.} and Gemma Modinos and Chen, {Kuan Ming} and Philip McGuire and Paul Allen",

year = "2015",

month = aug,

day = "1",

doi = "10.1016/j.neubiorev.2015.04.019",

language = "English",

volume = "55",

pages = "444--452",

journal = "Neuroscience and Biobehavioral Reviews",

issn = "0149-7634",

}

TY - JOUR

T1 - A systematic review of multisensory cognitive-affective integration in schizophrenia

AU - Tseng, Huai Hsuan

AU - Bossong, Matthijs G.

AU - Modinos, Gemma

AU - Chen, Kuan Ming

AU - McGuire, Philip

AU - Allen, Paul

PY - 2015/8/1

Y1 - 2015/8/1

N2 - The etymology of schizophrenia implies poor functional integration of sensory, cognitive and affective processes. Multisensory integration (MSI) is a spontaneous perceptual-cognitive process by which relevant information from multiple sensory modalities is extracted to generate a holistic experience. Deficits in MSI may hinder prompt and appropriate behavioural responses in a complex and transient environment. Despite extensive investigation of sensory, cognitive and affective processing in patients with schizophrenia, little is known about how MSI is affected in the illness. We systemically searched the PubMed electronic database and reviewed twenty-nine behavioural and neuroimaging studies examining MSI in patients with schizophrenia. The available evidence indicates impaired MSI for non-emotional stimuli in schizophrenia, especially for linguistic information. There is also evidence for altered MSI for emotional stimuli, although findings are inconsistent and may be modality-specific. Brain functional alterations in the superior temporal cortex and inferior frontal cortex appear to underlie the deficits in both non-emotional and emotional MSI. The limitations of the experimental paradigms used and directions for future research are also discussed.

AB - The etymology of schizophrenia implies poor functional integration of sensory, cognitive and affective processes. Multisensory integration (MSI) is a spontaneous perceptual-cognitive process by which relevant information from multiple sensory modalities is extracted to generate a holistic experience. Deficits in MSI may hinder prompt and appropriate behavioural responses in a complex and transient environment. Despite extensive investigation of sensory, cognitive and affective processing in patients with schizophrenia, little is known about how MSI is affected in the illness. We systemically searched the PubMed electronic database and reviewed twenty-nine behavioural and neuroimaging studies examining MSI in patients with schizophrenia. The available evidence indicates impaired MSI for non-emotional stimuli in schizophrenia, especially for linguistic information. There is also evidence for altered MSI for emotional stimuli, although findings are inconsistent and may be modality-specific. Brain functional alterations in the superior temporal cortex and inferior frontal cortex appear to underlie the deficits in both non-emotional and emotional MSI. The limitations of the experimental paradigms used and directions for future research are also discussed.

KW - Congruent facilitation

KW - Emotion

KW - Functional magnetic resonance imaging

KW - Incongruent interference

KW - Multi-sensory integration

KW - Schizophrenia

UR - http://www.scopus.com/inward/record.url?scp=84930942605&partnerID=8YFLogxK

U2 - 10.1016/j.neubiorev.2015.04.019

DO - 10.1016/j.neubiorev.2015.04.019

M3 - Article

AN - SCOPUS:84930942605

SN - 0149-7634

VL - 55

SP - 444

EP - 452

JO - Neuroscience and Biobehavioral Reviews

JF - Neuroscience and Biobehavioral Reviews

ER -

A systematic review of multisensory cognitive-affective integration in schizophrenia

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this