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A systematic review of the literature exploring the interplay between prostate cancer and type two diabetes mellitus

Research output: Contribution to journalReview article

Danielle Crawley, Florence Chamberlain, Hans Garmo, Sarah Rudman, Björn Zethelius, Lars Holmberg, Jan Adolfsson, Par E. Stattin, Paul Carroll, Mieke Van Hemelrijck

Original languageEnglish
Article number802
Journalecancermedicalscience
Volume12
DOIs
Published25 Jan 2018

King's Authors

Abstract

Prostate cancer (PCa) and type two diabetes mellitus (T2DM) are both increasing prevalent conditions and often occur concurrently. However, the relationship between the two is more complex than just two prevalent conditions co-existing. This review systematically explores the literature around the interplay between the two conditions. It covers the impact of pre-existing T2DM on PCa incidence, grade and stage, as well as exploring the impact of T2DM on PCa outcomes and mortality and the interaction between T2DM and PCa treatments.

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