Accelerated 3D T₂w-Imaging of the Prostate with 1-mm Isotropic Resolution in less than 3 minutes

TY - JOUR

T1 - Accelerated 3D T2w-Imaging of the Prostate with 1-mm Isotropic Resolution in less than 3 minutes

AU - Vidya Shankar, Rohini

AU - Roccia, Elisa

AU - Cruz, Gastao

AU - Neji, Radhouene

AU - Botnar, René

AU - Prezzi, Davide

AU - Goh, Vicky

AU - Prieto, Claudia

AU - Dregely, Isabel

N1 - © 2019 International Society for Magnetic Resonance in Medicine.

PY - 2019/8

Y1 - 2019/8

N2 - PURPOSE: To achieve 3D T2 w imaging of the prostate with 1-mm isotropic resolution in less than 3 min.METHODS: We devised and implemented a 3D T2 -prepared multishot balanced steady state free precession (T2 prep-bSSFP) acquisition sequence with a variable density undersampled trajectory combined with a total variation regularized iterative SENSE (TV-SENSE) reconstruction. Prospectively undersampled images of the prostate (acceleration factor R = 3) were acquired in 11 healthy subjects in an institutional review board-approved study. Image quality metrics (subjective signal-to-noise ratio, contrast, sharpness, and overall prostate image quality) were evaluated by 2 radiologists. Scores of the proposed accelerated sequence were compared using the Wilcoxon signed-rank and Kruskal-Wallis non-parametric tests to prostate images acquired using a fully sampled 3D T2 prep-bSSFP acquisition, and with clinical standard 2D and 3D turbo spin echo (TSE) T2 w acquisitions. A P-value < 0.05 was considered significant.RESULTS: The 3× accelerated 3D T2 prep-bSSFP images required a scan time (min:s) of 2:45, while the fully sampled 3D T2 prep-bSSFP and clinical standard 3D TSE images were acquired in 8:23 and 7:29, respectively. Image quality scores (contrast, sharpness, and overall prostate image quality) of the accelerated 3D T2 prep-bSSFP, fully sampled T2 prep-bSSFP, and clinical standard 3D TSE acquisitions along all 3 spatial dimensions were not significantly different (P > 0.05).CONCLUSION: 3D T2 w images of the prostate with 1-mm isotropic resolution can be acquired in less than 3 min, with image quality that is comparable to a clinical standard 3D TSE sequence but only takes a third of the acquisition time.

AB - PURPOSE: To achieve 3D T2 w imaging of the prostate with 1-mm isotropic resolution in less than 3 min.METHODS: We devised and implemented a 3D T2 -prepared multishot balanced steady state free precession (T2 prep-bSSFP) acquisition sequence with a variable density undersampled trajectory combined with a total variation regularized iterative SENSE (TV-SENSE) reconstruction. Prospectively undersampled images of the prostate (acceleration factor R = 3) were acquired in 11 healthy subjects in an institutional review board-approved study. Image quality metrics (subjective signal-to-noise ratio, contrast, sharpness, and overall prostate image quality) were evaluated by 2 radiologists. Scores of the proposed accelerated sequence were compared using the Wilcoxon signed-rank and Kruskal-Wallis non-parametric tests to prostate images acquired using a fully sampled 3D T2 prep-bSSFP acquisition, and with clinical standard 2D and 3D turbo spin echo (TSE) T2 w acquisitions. A P-value < 0.05 was considered significant.RESULTS: The 3× accelerated 3D T2 prep-bSSFP images required a scan time (min:s) of 2:45, while the fully sampled 3D T2 prep-bSSFP and clinical standard 3D TSE images were acquired in 8:23 and 7:29, respectively. Image quality scores (contrast, sharpness, and overall prostate image quality) of the accelerated 3D T2 prep-bSSFP, fully sampled T2 prep-bSSFP, and clinical standard 3D TSE acquisitions along all 3 spatial dimensions were not significantly different (P > 0.05).CONCLUSION: 3D T2 w images of the prostate with 1-mm isotropic resolution can be acquired in less than 3 min, with image quality that is comparable to a clinical standard 3D TSE sequence but only takes a third of the acquisition time.

KW - 3D prostate imaging

KW - T -weighted MRI

KW - TV-SENSE

KW - fast imaging

KW - isotropic resolution

UR - http://www.scopus.com/inward/record.url?scp=85064612852&partnerID=8YFLogxK

U2 - 10.1002/mrm.27764

DO - 10.1002/mrm.27764

M3 - Article

C2 - 31006906

SN - 0740-3194

VL - 82

SP - 721

EP - 731

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

IS - 2

ER -