Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis

CE Kleinrouweler; MMJ Wiegerinck; C Ris-Stalpers; PMM Bossuyt; JAM van der Post; P von Dadelszen; BWJ Mol; E Pajkrt; for the EBM CONNECT Collaboration

doi:10.1111/j.1471-0528.2012.03311.x

Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis

CE Kleinrouweler, MMJ Wiegerinck, C Ris-Stalpers, PMM Bossuyt, JAM van der Post, P von Dadelszen, BWJ Mol, E Pajkrt, for the EBM CONNECT Collaboration

Women & Children's Health

Research output: Contribution to journal › Article › peer-review

216 Citations (Scopus)

Abstract

Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis. BJOG 2012;119:778–787.Background Biomarkers have been proposed for identification of women at increased risk of developing pre-eclampsia.Objectives To investigate the capacity of circulating placental growth factor (PlGF), vascular endothelial growth factor (VEGF), soluble fms-like tyrosine kinase-1 (sFLT1) and soluble endoglin (sENG) to predict pre-eclampsia.Search strategy Medline and Embase through October 2010 and reference lists of reviews, without constraints.Selection criteria We included original publications on testing of PlGF, VEGF, sFLT1 and sENG in serum or plasma of pregnant women at

Original language	Undefined/Unknown
Pages (from-to)	778-787
Number of pages	10
Journal	BJOG
Volume	119
Issue number	7
DOIs	https://doi.org/10.1111/j.1471-0528.2012.03311.x
Publication status	Published - 2012

Keywords

Biomarkers, placental growth factor, pre-eclampsia, soluble endoglin, soluble fms-like tyrosine kinase-1, vascular endothelial growth factor

Access to Document

10.1111/j.1471-0528.2012.03311.x

http://dx.doi.org/10.1111/j.1471-0528.2012.03311.x

Cite this

Kleinrouweler, CE., Wiegerinck, MMJ., Ris-Stalpers, C., Bossuyt, PMM., van der Post, JAM., von Dadelszen, P., Mol, BWJ., Pajkrt, E., & Collaboration, F. T. EBM. CONNECT. (2012). Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis. BJOG, 119(7), 778-787. https://doi.org/10.1111/j.1471-0528.2012.03311.x

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abstract = "Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis. BJOG 2012;119:778–787.Background Biomarkers have been proposed for identification of women at increased risk of developing pre-eclampsia.Objectives To investigate the capacity of circulating placental growth factor (PlGF), vascular endothelial growth factor (VEGF), soluble fms-like tyrosine kinase-1 (sFLT1) and soluble endoglin (sENG) to predict pre-eclampsia.Search strategy Medline and Embase through October 2010 and reference lists of reviews, without constraints.Selection criteria We included original publications on testing of PlGF, VEGF, sFLT1 and sENG in serum or plasma of pregnant women at ",

keywords = "Biomarkers, placental growth factor, pre-eclampsia, soluble endoglin, soluble fms-like tyrosine kinase-1, vascular endothelial growth factor",

author = "CE Kleinrouweler and MMJ Wiegerinck and C Ris-Stalpers and PMM Bossuyt and {van der Post}, JAM and {von Dadelszen}, P and BWJ Mol and E Pajkrt and Collaboration, {for the EBM CONNECT}",

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Kleinrouweler, CE, Wiegerinck, MMJ, Ris-Stalpers, C, Bossuyt, PMM, van der Post, JAM, von Dadelszen, P, Mol, BWJ, Pajkrt, E & Collaboration, FTEBMCONNECT 2012, 'Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis', BJOG, vol. 119, no. 7, pp. 778-787. https://doi.org/10.1111/j.1471-0528.2012.03311.x

Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis. / Kleinrouweler, CE; Wiegerinck, MMJ; Ris-Stalpers, C et al.
In: BJOG, Vol. 119, No. 7, 2012, p. 778-787.

Research output: Contribution to journal › Article › peer-review

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Kleinrouweler CE, Wiegerinck MMJ, Ris-Stalpers C, Bossuyt PMM, van der Post JAM, von Dadelszen P et al. Accuracy of circulating placental growth factor, vascular endothelial growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in the prediction of pre-eclampsia: a systematic review and meta-analysis. BJOG. 2012;119(7):778-787. doi: 10.1111/j.1471-0528.2012.03311.x