Abstract
Bioassay-guided fractionation of Physocarpus capitatus yielded two new cucurbitacins (3 and 4) along with the known cucurbitacin F (1) and dihydrocucurbitacin F (2). Preliminary mechanism of action studies indicate that the cucurbitacins cause actin aggregates and inhibit cell division.
Original language | English |
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Pages (from-to) | 1927-1929 |
Number of pages | 3 |
Journal | Journal of Natural Products |
Volume | 71 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2008 |