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Actin Dynamics and HIV-1 Entry

Research output: Contribution to journalShort survey

Sergi Padilla-Parra, Michael L. Dustin

Original languageEnglish
Pages (from-to)354-356
Number of pages3
JournalTRENDS IN MOLECULAR MEDICINE
Volume22
Issue number5
DOIs
Publication statusPublished - 1 May 2016

King's Authors

Abstract

Cortical F-actin plays important roles during HIV-1 infection. A recent paper in Cell highlights the involvement of F-actin in enhancing dendritic cell (DC)-mediated HIV-1 infection of T cells. Such a critical mechanism of HIV-1 trans-enhancement between human DCs and T cells had not been analyzed in molecular detail before this work.

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