Activation and 3D Imaging of Phase-change Nanodroplet Contrast Agents with a 2D Ultrasound Probe

Sevan Harput; Ge Zhang; Matthieu Toulemonde; Jiaqi Zhu; Kirsten Christensen-Jeffries; Jemma Brown; Robert J. Eckersley; Chris Dunsby; Meng Xing Tang

doi:10.1109/ULTSYM.2019.8925892

Activation and 3D Imaging of Phase-change Nanodroplet Contrast Agents with a 2D Ultrasound Probe

Sevan Harput, Ge Zhang, Matthieu Toulemonde, Jiaqi Zhu, Kirsten Christensen-Jeffries, Jemma Brown, Robert J. Eckersley, Chris Dunsby, Meng Xing Tang

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Citations (Scopus)

Abstract

Nanodroplets are on-demand ultrasound contrast agents. They can remain in circulation longer in vivo than mi-crobubbles and can be spatiotemporally and selectively activated to provide contrast when required. Perfluorocarbon nanodroplets have been used for conventional 2D ultrasound imaging and different types of nanodroplets have been studied and characterized by researchers regarding their suitability for imaging. However, the use of nanodroplets for 3D imaging and their activation using a 2D ultrasound probe has not been reported. In this study, we investigate the nanodroplet activation using a 2D ultrasound imaging probe within clinical safety limits.

Original language	English
Title of host publication	2019 IEEE International Ultrasonics Symposium, IUS 2019
Publisher	IEEE Computer Society
Pages	2275-2278
Number of pages	4
Volume	2019-October
ISBN (Electronic)	9781728145969
DOIs	https://doi.org/10.1109/ULTSYM.2019.8925892
Publication status	Published - 1 Oct 2019
Event	2019 IEEE International Ultrasonics Symposium, IUS 2019 - Glasgow, United Kingdom Duration: 6 Oct 2019 → 9 Oct 2019

Conference

Conference	2019 IEEE International Ultrasonics Symposium, IUS 2019
Country/Territory	United Kingdom
City	Glasgow
Period	6/10/2019 → 9/10/2019

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10.1109/ULTSYM.2019.8925892

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Harput, S., Zhang, G., Toulemonde, M., Zhu, J., Christensen-Jeffries, K., Brown, J., Eckersley, R. J., Dunsby, C., & Tang, M. X. (2019). Activation and 3D Imaging of Phase-change Nanodroplet Contrast Agents with a 2D Ultrasound Probe. In 2019 IEEE International Ultrasonics Symposium, IUS 2019 (Vol. 2019-October, pp. 2275-2278). Article 8925892 IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2019.8925892

@inproceedings{6d1aa18e8472431990e0062696ba2643,

title = "Activation and 3D Imaging of Phase-change Nanodroplet Contrast Agents with a 2D Ultrasound Probe",

abstract = "Nanodroplets are on-demand ultrasound contrast agents. They can remain in circulation longer in vivo than mi-crobubbles and can be spatiotemporally and selectively activated to provide contrast when required. Perfluorocarbon nanodroplets have been used for conventional 2D ultrasound imaging and different types of nanodroplets have been studied and characterized by researchers regarding their suitability for imaging. However, the use of nanodroplets for 3D imaging and their activation using a 2D ultrasound probe has not been reported. In this study, we investigate the nanodroplet activation using a 2D ultrasound imaging probe within clinical safety limits.",

author = "Sevan Harput and Ge Zhang and Matthieu Toulemonde and Jiaqi Zhu and Kirsten Christensen-Jeffries and Jemma Brown and Eckersley, {Robert J.} and Chris Dunsby and Tang, {Meng Xing}",

year = "2019",

month = oct,

day = "1",

doi = "10.1109/ULTSYM.2019.8925892",

language = "English",

volume = "2019-October",

pages = "2275--2278",

booktitle = "2019 IEEE International Ultrasonics Symposium, IUS 2019",

publisher = "IEEE Computer Society",

note = "2019 IEEE International Ultrasonics Symposium, IUS 2019 ; Conference date: 06-10-2019 Through 09-10-2019",

}

Harput, S, Zhang, G, Toulemonde, M, Zhu, J, Christensen-Jeffries, K , Brown, J , Eckersley, RJ, Dunsby, C & Tang, MX 2019, Activation and 3D Imaging of Phase-change Nanodroplet Contrast Agents with a 2D Ultrasound Probe. in 2019 IEEE International Ultrasonics Symposium, IUS 2019. vol. 2019-October, 8925892, IEEE Computer Society, pp. 2275-2278, 2019 IEEE International Ultrasonics Symposium, IUS 2019, Glasgow, United Kingdom, 6/10/2019. https://doi.org/10.1109/ULTSYM.2019.8925892

Activation and 3D Imaging of Phase-change Nanodroplet Contrast Agents with a 2D Ultrasound Probe. / Harput, Sevan; Zhang, Ge; Toulemonde, Matthieu et al.
2019 IEEE International Ultrasonics Symposium, IUS 2019. Vol. 2019-October IEEE Computer Society, 2019. p. 2275-2278 8925892.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Harput, Sevan

AU - Zhang, Ge

AU - Toulemonde, Matthieu

AU - Zhu, Jiaqi

AU - Christensen-Jeffries, Kirsten

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AU - Eckersley, Robert J.

AU - Dunsby, Chris

AU - Tang, Meng Xing

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N2 - Nanodroplets are on-demand ultrasound contrast agents. They can remain in circulation longer in vivo than mi-crobubbles and can be spatiotemporally and selectively activated to provide contrast when required. Perfluorocarbon nanodroplets have been used for conventional 2D ultrasound imaging and different types of nanodroplets have been studied and characterized by researchers regarding their suitability for imaging. However, the use of nanodroplets for 3D imaging and their activation using a 2D ultrasound probe has not been reported. In this study, we investigate the nanodroplet activation using a 2D ultrasound imaging probe within clinical safety limits.

AB - Nanodroplets are on-demand ultrasound contrast agents. They can remain in circulation longer in vivo than mi-crobubbles and can be spatiotemporally and selectively activated to provide contrast when required. Perfluorocarbon nanodroplets have been used for conventional 2D ultrasound imaging and different types of nanodroplets have been studied and characterized by researchers regarding their suitability for imaging. However, the use of nanodroplets for 3D imaging and their activation using a 2D ultrasound probe has not been reported. In this study, we investigate the nanodroplet activation using a 2D ultrasound imaging probe within clinical safety limits.

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BT - 2019 IEEE International Ultrasonics Symposium, IUS 2019

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ER -

Activation and 3D Imaging of Phase-change Nanodroplet Contrast Agents with a 2D Ultrasound Probe

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