Adherence to long-term anticoagulation treatment, what is known and what the future might hold

TY - JOUR

T1 - Adherence to long-term anticoagulation treatment, what is known and what the future might hold

AU - Abdou, John K

AU - Auyeung, Vivian

AU - Patel, Jignesh P

AU - Arya, Roopen

PY - 2016/6/22

Y1 - 2016/6/22

N2 - Adherence to medication, commonly reported as being 50% in chronic diseases, is of great concern in healthcare. Medication non-adherence is particularly apparent in chronic diseases, where treatment is often preventative and may provide little or no symptomatic relief or feedback for the patient. A lot of research has been undertaken to describe the extent of non-adherence to long-term anticoagulation therapy, particularly with vitamin K antagonists and more recently with direct oral anticoagulants. However, the literature is scarce with respect to describing adherence to anticoagulation in terms of the behavioural aspects that influence medicine use. Utilizing the COM-B (capability, opportunity, motivation and behaviour) psychological model of non-adherence, we present the available evidence, not only in terms of describing the extent of the non-adherence problem, but also describing why patients do not adhere, offering theory-driven and evidence-based solutions to improve long-term adherence to chronic anticoagulation therapy. Lessons learned are not only applicable within the field of anticoagulation but throughout haematology.

AB - Adherence to medication, commonly reported as being 50% in chronic diseases, is of great concern in healthcare. Medication non-adherence is particularly apparent in chronic diseases, where treatment is often preventative and may provide little or no symptomatic relief or feedback for the patient. A lot of research has been undertaken to describe the extent of non-adherence to long-term anticoagulation therapy, particularly with vitamin K antagonists and more recently with direct oral anticoagulants. However, the literature is scarce with respect to describing adherence to anticoagulation in terms of the behavioural aspects that influence medicine use. Utilizing the COM-B (capability, opportunity, motivation and behaviour) psychological model of non-adherence, we present the available evidence, not only in terms of describing the extent of the non-adherence problem, but also describing why patients do not adhere, offering theory-driven and evidence-based solutions to improve long-term adherence to chronic anticoagulation therapy. Lessons learned are not only applicable within the field of anticoagulation but throughout haematology.

KW - Adherence to medication

KW - ANTICOAGULATION

KW - WARFARIN

KW - novel oral anticoagulant

KW - HEALTH PSYCHOLOGY

KW - health beliefs

KW - Medication beliefs

UR - http://www.scopus.com/inward/record.url?scp=84976512811&partnerID=8YFLogxK

U2 - 10.1111/bjh.14134

DO - 10.1111/bjh.14134

M3 - Article

SN - 0007-1048

JO - British Journal of Haematology

JF - British Journal of Haematology

ER -