Adrenal scintigraphy with 75Se selenonorcholestenol: a review

TY - JOUR

T1 - Adrenal scintigraphy with 75Se selenonorcholestenol

T2 - a review

AU - Sudell, C J

AU - Blake, G M

AU - Gossage, A A

AU - Cullen, D R

AU - Munro, D S

PY - 1985/9

Y1 - 1985/9

N2 - We have reviewed 58 patients on whom adrenal scintigraphy has been performed using 75Se selenonorcholestenol. For 15 patients whose adrenal function was biochemically normal, the upper limit of normal of the 7 day adrenal uptake test was 0.45%, considerably higher than the generally accepted value of 0.3%. There is evidence from this group of patients that stress and obesity might account for uptakes in the range 0.3-0.45%. The sensitivity of the uptake test is poor, with 7 out of 23 patients with Cushing's syndrome having uptakes within the normal range. Scintigraphy of such patients may still be useful in differentiating between unilateral and bilateral adrenal involvement.

AB - We have reviewed 58 patients on whom adrenal scintigraphy has been performed using 75Se selenonorcholestenol. For 15 patients whose adrenal function was biochemically normal, the upper limit of normal of the 7 day adrenal uptake test was 0.45%, considerably higher than the generally accepted value of 0.3%. There is evidence from this group of patients that stress and obesity might account for uptakes in the range 0.3-0.45%. The sensitivity of the uptake test is poor, with 7 out of 23 patients with Cushing's syndrome having uptakes within the normal range. Scintigraphy of such patients may still be useful in differentiating between unilateral and bilateral adrenal involvement.

M3 - Article

C2 - 4069475

SN - 0143-3636

VL - 6

SP - 519

EP - 528

JO - Nuclear Medicine Communications

JF - Nuclear Medicine Communications

IS - 9

M1 - N/A

ER -