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Adrenoceptors antagonists for the prevention and treatment of neurodegenerative conditions

Research output: Patent

Gennaro Pagano (Inventor), Michele Tagliati (Inventor)

Original languageEnglish
Patent numberEP3013342 A2
IPCPCT/US2014/044715
Priority date27/06/2013
Publication statusPublished - 26 Feb 2015

King's Authors

Abstract

The present disclosure teaches methods for treating and preventing a variety of neurodegenerative conditions and symptoms associated therewith, including Alzheimer's disease (AD) and idiopathic Parkinson's disease (iPD), by utilizing adrenoceptor antagonists. Adrenoceptor antagonists that can be used include β-blockers, such as acebutolol, betaxolol, bisopropolol, bopindolol, carvedilol, metoprolol, oxprenolol, propranolol, and timolol. The present disclosure also teaches methods for diagnosing and monitoring the progression of iPD.

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