Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy

D. D U Li; S. Poland; S. Coelho; D. Tyndall; W. Zhang; J. Richardson; R. K. Henderson; S. M. Ameer-Beg

doi:10.1109/EMBC.2013.6610180

Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy

D. D U Li, S. Poland, S. Coelho, D. Tyndall, W. Zhang, J. Richardson, R. K. Henderson, S. M. Ameer-Beg

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

Abstract

We have developed a fast hardware friendly bi-exponential fluorescence lifetime algorithm suitable for 2D CMOS single-photon avalanche diode (SPAD) arrays. The performance of the proposed algorithm against other techniques is demonstrated on the data from a plant specimen (Convallaria) by using 0.13μm CMOS SPAD arrays mounted on a multi-beam multi-photon microscopy system.

Original language	English
Title of host publication	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages	3036-3039
Number of pages	4
DOIs	https://doi.org/10.1109/EMBC.2013.6610180
Publication status	Published - 2013
Event	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan Duration: 3 Jul 2013 → 7 Jul 2013

Conference

Conference	2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Country/Territory	Japan
City	Osaka
Period	3/07/2013 → 7/07/2013

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10.1109/EMBC.2013.6610180

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Li, D. D. U., Poland, S., Coelho, S., Tyndall, D., Zhang, W., Richardson, J., Henderson, R. K., & Ameer-Beg, S. M. (2013). Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 3036-3039). Article 6610180 https://doi.org/10.1109/EMBC.2013.6610180

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title = "Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy",

abstract = "We have developed a fast hardware friendly bi-exponential fluorescence lifetime algorithm suitable for 2D CMOS single-photon avalanche diode (SPAD) arrays. The performance of the proposed algorithm against other techniques is demonstrated on the data from a plant specimen (Convallaria) by using 0.13μm CMOS SPAD arrays mounted on a multi-beam multi-photon microscopy system.",

author = "Li, {D. D U} and S. Poland and S. Coelho and D. Tyndall and W. Zhang and J. Richardson and Henderson, {R. K.} and Ameer-Beg, {S. M.}",

year = "2013",

doi = "10.1109/EMBC.2013.6610180",

language = "English",

isbn = "9781457702167",

pages = "3036--3039",

booktitle = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",

note = "2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 ; Conference date: 03-07-2013 Through 07-07-2013",

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Li, DDU, Poland, S, Coelho, S, Tyndall, D, Zhang, W, Richardson, J, Henderson, RK & Ameer-Beg, SM 2013, Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS., 6610180, pp. 3036-3039, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 3/07/2013. https://doi.org/10.1109/EMBC.2013.6610180

Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy. / Li, D. D U; Poland, S.; Coelho, S. et al.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2013. p. 3036-3039 6610180.

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

TY - CHAP

T1 - Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy

AU - Li, D. D U

AU - Poland, S.

AU - Coelho, S.

AU - Tyndall, D.

AU - Zhang, W.

AU - Richardson, J.

AU - Henderson, R. K.

AU - Ameer-Beg, S. M.

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AB - We have developed a fast hardware friendly bi-exponential fluorescence lifetime algorithm suitable for 2D CMOS single-photon avalanche diode (SPAD) arrays. The performance of the proposed algorithm against other techniques is demonstrated on the data from a plant specimen (Convallaria) by using 0.13μm CMOS SPAD arrays mounted on a multi-beam multi-photon microscopy system.

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SN - 9781457702167

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BT - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

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Y2 - 3 July 2013 through 7 July 2013

ER -

Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy

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