Advances in capillary electrochromatography and micro-high performance liquid chromatography monolithic columns for separation science

C Legido-Quigley, N D Marlin, V Melin, A Manz, N W Smith

Research output: Contribution to journalLiterature reviewpeer-review

212 Citations (Scopus)

Abstract

Over the last decade, monoliths or continuous beds have emerged as an alternative to traditional packed-bed columns for use in capillary electrochromatography (CEC) and micro-high performance liquid chromatography (mu-HPLC). Monolithic columns can be divided into two categories: silica-based monolithic columns and rigid organic polymer-based monolithic columns resulting from the polymerization of acrylamide, styrene, acrylate or methacrylate monomers. In this paper, the chemistry and most recent applications of these various types of monoliths in both CEC and mu-HPLC are presented.
Original languageEnglish
Pages (from-to)917 - 944
Number of pages28
JournalElectrophoresis
Volume24
Issue number6
Publication statusPublished - Mar 2003

Fingerprint

Dive into the research topics of 'Advances in capillary electrochromatography and micro-high performance liquid chromatography monolithic columns for separation science'. Together they form a unique fingerprint.

Cite this