Advances in molecular imaging of atherosclerosis and myocardial infarction: shedding new light on in vivo cardiovascular biology

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Abstract

Molecular imaging of the cardiovascular system heavily relies on the development of new imaging probes and technologies to facilitate visualization of biological processes underlying or preceding disease. Molecular imaging is a highly active research discipline that has seen tremendous growth over the past decade. It has broadened our understanding of oncologic, neurologic, and cardiovascular diseases by providing new insights into the in vivo biology of disease progression and therapeutic interventions. As it allows for the longitudinal evaluation of biological processes, it is ideally suited for monitoring treatment response. In this review, we will concentrate on the major accomplishments and advances in the field of molecular imaging of atherosclerosis and myocardial infarction with a special focus on magnetic resonance imaging.
Original languageEnglish
Article numberN/A
Pages (from-to)H1397-H1410
Number of pages14
JournalAMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Volume303
Issue number12
Early online date12 Oct 2012
DOIs
Publication statusPublished - 15 Dec 2012

Keywords

  • Animals
  • Apoptosis
  • Atherosclerosis
  • Disease Models, Animal
  • Humans
  • Magnetic Resonance Imaging
  • Molecular Imaging
  • Myocardial Infarction
  • Necrosis
  • Positron-Emission Tomography
  • Tomography, Emission-Computed, Single-Photon

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