All-optical multimode fibre photoacoustic endomicroscopy with scalable spatial resolution and field-of-view

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Abstract

An all-optical, forward-viewing, optical-resolution photoacoustic endomicroscopy probe was developed for guiding minimally invasive procedures. The probe comprises a multimode fibre for the delivery of excitation laser via wavefront shaping, and a fibre-optic ultrasound sensor based on a plane-concave microresonator at the tip of a single-mode fibre. High-resolution photoacoustic microscopy images of mouse red blood cells and mouse ear vasculature were acquired, and the high scalability of the probe in terms of field-of-view and spatial resolution was demonstrated. The ultrathin photoacoustic endomicroscopy probe promises to guide minimally invasive surgery by providing both molecular and microstructural information.
Original languageEnglish
Title of host publicationProc. SPIE 12631
PublisherSPIE
Number of pages3
Publication statusPublished - 11 Aug 2023

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