TY - JOUR
T1 - AllergoOncology: Generating a canine anti-cancer IgE against the epidermal growth factor receptor (EGFR)
T2 - Generating a canine anticancer IgE against the epidermal growth factor receptor
AU - Fazekas-Singer, Judit
AU - Singer, Josef
AU - Ilieva, Kristina M.
AU - Matz, Miroslawa
AU - Herrmann, Ina
AU - Spillner, Edzard
AU - Karagiannis, Sophia N.
AU - Jensen-Jarolim, Erika
N1 - Copyright © 2018. Published by Elsevier Inc.
PY - 2018/5/7
Y1 - 2018/5/7
N2 - Anti-cancer immunotherapies currently rely on IgG antibodies. In line with the AllergoOncology concept we provide evidence that tumor-specific IgE, alone or combined with IgG, may be superior to IgG treatment alone. The novel can225IgE-λ was made for future studies in dogs as translational model patients.
AB - Anti-cancer immunotherapies currently rely on IgG antibodies. In line with the AllergoOncology concept we provide evidence that tumor-specific IgE, alone or combined with IgG, may be superior to IgG treatment alone. The novel can225IgE-λ was made for future studies in dogs as translational model patients.
U2 - 10.1016/j.jaci.2018.04.021
DO - 10.1016/j.jaci.2018.04.021
M3 - Letter
C2 - 29746883
SN - 0091-6749
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
ER -