TY - JOUR
T1 - An observational retrospective study of odontogenic cyst´s and tumours over an 18-year period in a portuguese population according to the new who head and neck tumour classification
AU - Monteiro, Luis
AU - Santiago, Catarina
AU - Do Amaral, Barbas
AU - Al-Mossallami, Azza
AU - Albuquerque, Rui
AU - Lopes, Carlos
N1 - Funding Information:
The authors would like to thank to the Pathology Department, Stomatology Department and also to all Archive Department professionals for excellent assistance in this study. This work was part of a project (05-GCD-CICS-2011) from Cooperativa de Ensino Superior Polit?cnico e Universit?rio (CESPU).
Publisher Copyright:
© Medicina Oral S. L. C.I.F. B.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/7
Y1 - 2021/7
N2 - Background: Odontogenic cysts and tumours of the jaws represent one of the most prevalent groups of oral-maxillofacial lesions. We aimed to evaluate the clinical and pathological characteristics of a cohort of odontogenic cysts (OC) and odontogenic tumours (OT) of the jaws in a Portuguese population. Material and Methods: This observational retrospective study analysed patients diagnosed with either an OC or OT of the jaws at a central hospital of Oporto, Portugal, between 1988 and 2006. Data collected from patients’ files included demographic, clinical, radiological and histopathological information. Recurrence was evaluated using univariate and multivariate analysis. Results: The sample consisted of 397 patients, 231 males (58.2%) and 166 females (41.8%), with a mean-age of 36.7±17 years. Twenty-seven patients (6.8%) presented with more than one lesion providing a total of 433 lesions. There were 396 (91.5%) OC, mostly represented by radicular cysts (n=257;59.4%), dentigerous cysts (n=79;18.2%), or odontogenic keratocysts (n=50;11.5%). There were 37 (8.5%) OT, mostly represented by amelo-blastomas (n=16;3.7%), and odontomas (n=9;2.1%). The most common initial clinical manifestation was swelling (n=224;51.7%). Recurrence was observed in 30 cases (6.9%), mostly in ameloblastomas (n=6;37.5%) and odontogenic keratocysts (n=12;24%). In the multivariate analysis the diagnosis classification of the lesion was the only indepen-dent and significant variable related with the recurrence (P=0.04). Conclusions: Radicular cysts were the most commonly occurring type of OC and ameloblastomas the most commonly occurring OT. Amelobastomas and odontogenic keratocysts were the lesions with the highest rates of recur-rence. This large sample provides useful information about the frequency profile and characteristics of OC and OT over a period of 18 years, allowing valuable comparison with data from other countries.
AB - Background: Odontogenic cysts and tumours of the jaws represent one of the most prevalent groups of oral-maxillofacial lesions. We aimed to evaluate the clinical and pathological characteristics of a cohort of odontogenic cysts (OC) and odontogenic tumours (OT) of the jaws in a Portuguese population. Material and Methods: This observational retrospective study analysed patients diagnosed with either an OC or OT of the jaws at a central hospital of Oporto, Portugal, between 1988 and 2006. Data collected from patients’ files included demographic, clinical, radiological and histopathological information. Recurrence was evaluated using univariate and multivariate analysis. Results: The sample consisted of 397 patients, 231 males (58.2%) and 166 females (41.8%), with a mean-age of 36.7±17 years. Twenty-seven patients (6.8%) presented with more than one lesion providing a total of 433 lesions. There were 396 (91.5%) OC, mostly represented by radicular cysts (n=257;59.4%), dentigerous cysts (n=79;18.2%), or odontogenic keratocysts (n=50;11.5%). There were 37 (8.5%) OT, mostly represented by amelo-blastomas (n=16;3.7%), and odontomas (n=9;2.1%). The most common initial clinical manifestation was swelling (n=224;51.7%). Recurrence was observed in 30 cases (6.9%), mostly in ameloblastomas (n=6;37.5%) and odontogenic keratocysts (n=12;24%). In the multivariate analysis the diagnosis classification of the lesion was the only indepen-dent and significant variable related with the recurrence (P=0.04). Conclusions: Radicular cysts were the most commonly occurring type of OC and ameloblastomas the most commonly occurring OT. Amelobastomas and odontogenic keratocysts were the lesions with the highest rates of recur-rence. This large sample provides useful information about the frequency profile and characteristics of OC and OT over a period of 18 years, allowing valuable comparison with data from other countries.
KW - Ameloblastoma
KW - Dentigerous cyst
KW - Odontogenic cysts and tumours
KW - Odontogenic keratocyst
KW - Radicular cyst
KW - Recurrence
UR - http://www.scopus.com/inward/record.url?scp=85104070303&partnerID=8YFLogxK
U2 - 10.4317/medoral.24337
DO - 10.4317/medoral.24337
M3 - Article
C2 - 33340074
AN - SCOPUS:85104070303
SN - 1698-4447
VL - 26
SP - e482-e493
JO - Medicina Oral Patologia Oral Y Cirugia Bucal
JF - Medicina Oral Patologia Oral Y Cirugia Bucal
IS - 4
M1 - 24337
ER -