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An observational retrospective study of odontogenic cyst´s and tumours over an 18-year period in a portuguese population according to the new who head and neck tumour classification

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Luis Monteiro, Catarina Santiago, Barbas Do Amaral, Azza Al-Mossallami, Rui Albuquerque, Carlos Lopes

Original languageEnglish
Article number24337
Pages (from-to)e482-e493
JournalMedicina Oral Patologia Oral Y Cirugia Bucal
Volume26
Issue number4
DOIs
PublishedJul 2021

Bibliographical note

Funding Information: The authors would like to thank to the Pathology Department, Stomatology Department and also to all Archive Department professionals for excellent assistance in this study. This work was part of a project (05-GCD-CICS-2011) from Cooperativa de Ensino Superior Polit?cnico e Universit?rio (CESPU). Publisher Copyright: © Medicina Oral S. L. C.I.F. B. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

King's Authors

Abstract

Background: Odontogenic cysts and tumours of the jaws represent one of the most prevalent groups of oral-maxillofacial lesions. We aimed to evaluate the clinical and pathological characteristics of a cohort of odontogenic cysts (OC) and odontogenic tumours (OT) of the jaws in a Portuguese population. Material and Methods: This observational retrospective study analysed patients diagnosed with either an OC or OT of the jaws at a central hospital of Oporto, Portugal, between 1988 and 2006. Data collected from patients’ files included demographic, clinical, radiological and histopathological information. Recurrence was evaluated using univariate and multivariate analysis. Results: The sample consisted of 397 patients, 231 males (58.2%) and 166 females (41.8%), with a mean-age of 36.7±17 years. Twenty-seven patients (6.8%) presented with more than one lesion providing a total of 433 lesions. There were 396 (91.5%) OC, mostly represented by radicular cysts (n=257;59.4%), dentigerous cysts (n=79;18.2%), or odontogenic keratocysts (n=50;11.5%). There were 37 (8.5%) OT, mostly represented by amelo-blastomas (n=16;3.7%), and odontomas (n=9;2.1%). The most common initial clinical manifestation was swelling (n=224;51.7%). Recurrence was observed in 30 cases (6.9%), mostly in ameloblastomas (n=6;37.5%) and odontogenic keratocysts (n=12;24%). In the multivariate analysis the diagnosis classification of the lesion was the only indepen-dent and significant variable related with the recurrence (P=0.04). Conclusions: Radicular cysts were the most commonly occurring type of OC and ameloblastomas the most commonly occurring OT. Amelobastomas and odontogenic keratocysts were the lesions with the highest rates of recur-rence. This large sample provides useful information about the frequency profile and characteristics of OC and OT over a period of 18 years, allowing valuable comparison with data from other countries.

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