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An update on migraine: current understanding and future directions

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An update on migraine : current understanding and future directions. / Puledda, Francesca; Messina, Roberta; Goadsby, Peter J.

In: Journal of Neurology, Vol. 264, No. 9, 01.09.2017, p. 2031-2039.

Research output: Contribution to journalArticle

Harvard

Puledda, F, Messina, R & Goadsby, PJ 2017, 'An update on migraine: current understanding and future directions', Journal of Neurology, vol. 264, no. 9, pp. 2031-2039. https://doi.org/10.1007/s00415-017-8434-y

APA

Puledda, F., Messina, R., & Goadsby, P. J. (2017). An update on migraine: current understanding and future directions. Journal of Neurology, 264(9), 2031-2039. https://doi.org/10.1007/s00415-017-8434-y

Vancouver

Puledda F, Messina R, Goadsby PJ. An update on migraine: current understanding and future directions. Journal of Neurology. 2017 Sep 1;264(9):2031-2039. https://doi.org/10.1007/s00415-017-8434-y

Author

Puledda, Francesca ; Messina, Roberta ; Goadsby, Peter J. / An update on migraine : current understanding and future directions. In: Journal of Neurology. 2017 ; Vol. 264, No. 9. pp. 2031-2039.

Bibtex Download

@article{0d9ce4d3c6ca497c9b30e316c364d5d1,
title = "An update on migraine: current understanding and future directions",
abstract = "Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase in the interest around migraine pathophysiology has allowed researchers to unravel certain neurophysiological mechanisms and neurotransmitter involvement culminating in the recent development of novel therapies, which might substantially change the clinical approach to migraine patients. The present review will highlight the current aspects of migraine pathophysiology, covering an understanding of the complex workings of the migraine state and the brain regions responsible for them. We will further discuss the therapeutic agents which have appeared in the most recent years for migraine care, from calcitonin gene-related peptide (CGRP) receptor antagonists, gepants; through serotonin 5-HT1F receptor agonists, ditans, and CGRP or CGRP receptor monoclonal antibodies to invasive and non-invasive neuromodulation techniques.",
keywords = "CGRP, Migraine, Neuromodulation, Pathophysiology, Treatment",
author = "Francesca Puledda and Roberta Messina and Goadsby, {Peter J.}",
year = "2017",
month = "9",
day = "1",
doi = "10.1007/s00415-017-8434-y",
language = "English",
volume = "264",
pages = "2031--2039",
journal = "Journal of Neurology",
issn = "0340-5354",
publisher = "D. Steinkopff-Verlag",
number = "9",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - An update on migraine

T2 - current understanding and future directions

AU - Puledda, Francesca

AU - Messina, Roberta

AU - Goadsby, Peter J.

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase in the interest around migraine pathophysiology has allowed researchers to unravel certain neurophysiological mechanisms and neurotransmitter involvement culminating in the recent development of novel therapies, which might substantially change the clinical approach to migraine patients. The present review will highlight the current aspects of migraine pathophysiology, covering an understanding of the complex workings of the migraine state and the brain regions responsible for them. We will further discuss the therapeutic agents which have appeared in the most recent years for migraine care, from calcitonin gene-related peptide (CGRP) receptor antagonists, gepants; through serotonin 5-HT1F receptor agonists, ditans, and CGRP or CGRP receptor monoclonal antibodies to invasive and non-invasive neuromodulation techniques.

AB - Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase in the interest around migraine pathophysiology has allowed researchers to unravel certain neurophysiological mechanisms and neurotransmitter involvement culminating in the recent development of novel therapies, which might substantially change the clinical approach to migraine patients. The present review will highlight the current aspects of migraine pathophysiology, covering an understanding of the complex workings of the migraine state and the brain regions responsible for them. We will further discuss the therapeutic agents which have appeared in the most recent years for migraine care, from calcitonin gene-related peptide (CGRP) receptor antagonists, gepants; through serotonin 5-HT1F receptor agonists, ditans, and CGRP or CGRP receptor monoclonal antibodies to invasive and non-invasive neuromodulation techniques.

KW - CGRP

KW - Migraine

KW - Neuromodulation

KW - Pathophysiology

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=85029063849&partnerID=8YFLogxK

U2 - 10.1007/s00415-017-8434-y

DO - 10.1007/s00415-017-8434-y

M3 - Article

AN - SCOPUS:85029063849

VL - 264

SP - 2031

EP - 2039

JO - Journal of Neurology

JF - Journal of Neurology

SN - 0340-5354

IS - 9

ER -

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