Antioxidant and antimicrobial activities of Onosma argentatum and Rubia peregrina

U Ozgen; P J Houghton; Y Ogundipe; M Coskun

doi:10.1016/S0367-326X(03)00161-8

Antioxidant and antimicrobial activities of Onosma argentatum and Rubia peregrina

U Ozgen, P J Houghton, Y Ogundipe, M Coskun

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68 Citations (Scopus)

Abstract

The n-hexane-dichloromethane (1:1) extract of the roots of Onosma argentatum and the methanol extract (partitioned between water and chloroform, ethyl acetate and n-butanol, respectively), of the underground parts (roots and rhizomes) of Rubia peregrina were tested in vitro for their antioxidant and antimicrobial activities. The highest antioxidant activity (98%) was observed at 0.1% concentration for the roots of O. argentatum. It was 96% at 0.25% concentration on the ethyl acetate fraction of R. peregrina. O. argentatum extract was effective on Staphyloccoccus aureus, Bacillus subtilis and Escherichia coli. The ethyl acetate and chloroform fractions of R. peregrina were effective on S. aureus and E. coli, respectively. These two species did not have any antifungal activity. (C) 2003 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	682 - 685
Number of pages	4
Journal	FITOTERAPIA
Volume	74
Issue number	7-8
DOIs	https://doi.org/10.1016/S0367-326X(03)00161-8
Publication status	Published - Dec 2003

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title = "Antioxidant and antimicrobial activities of Onosma argentatum and Rubia peregrina",

abstract = "The n-hexane-dichloromethane (1:1) extract of the roots of Onosma argentatum and the methanol extract (partitioned between water and chloroform, ethyl acetate and n-butanol, respectively), of the underground parts (roots and rhizomes) of Rubia peregrina were tested in vitro for their antioxidant and antimicrobial activities. The highest antioxidant activity (98%) was observed at 0.1% concentration for the roots of O. argentatum. It was 96% at 0.25% concentration on the ethyl acetate fraction of R. peregrina. O. argentatum extract was effective on Staphyloccoccus aureus, Bacillus subtilis and Escherichia coli. The ethyl acetate and chloroform fractions of R. peregrina were effective on S. aureus and E. coli, respectively. These two species did not have any antifungal activity. (C) 2003 Elsevier B.V. All rights reserved.",

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T1 - Antioxidant and antimicrobial activities of Onosma argentatum and Rubia peregrina

AU - Ozgen, U

AU - Houghton, P J

AU - Ogundipe, Y

AU - Coskun, M

PY - 2003/12

Y1 - 2003/12

N2 - The n-hexane-dichloromethane (1:1) extract of the roots of Onosma argentatum and the methanol extract (partitioned between water and chloroform, ethyl acetate and n-butanol, respectively), of the underground parts (roots and rhizomes) of Rubia peregrina were tested in vitro for their antioxidant and antimicrobial activities. The highest antioxidant activity (98%) was observed at 0.1% concentration for the roots of O. argentatum. It was 96% at 0.25% concentration on the ethyl acetate fraction of R. peregrina. O. argentatum extract was effective on Staphyloccoccus aureus, Bacillus subtilis and Escherichia coli. The ethyl acetate and chloroform fractions of R. peregrina were effective on S. aureus and E. coli, respectively. These two species did not have any antifungal activity. (C) 2003 Elsevier B.V. All rights reserved.

AB - The n-hexane-dichloromethane (1:1) extract of the roots of Onosma argentatum and the methanol extract (partitioned between water and chloroform, ethyl acetate and n-butanol, respectively), of the underground parts (roots and rhizomes) of Rubia peregrina were tested in vitro for their antioxidant and antimicrobial activities. The highest antioxidant activity (98%) was observed at 0.1% concentration for the roots of O. argentatum. It was 96% at 0.25% concentration on the ethyl acetate fraction of R. peregrina. O. argentatum extract was effective on Staphyloccoccus aureus, Bacillus subtilis and Escherichia coli. The ethyl acetate and chloroform fractions of R. peregrina were effective on S. aureus and E. coli, respectively. These two species did not have any antifungal activity. (C) 2003 Elsevier B.V. All rights reserved.

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DO - 10.1016/S0367-326X(03)00161-8

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JF - FITOTERAPIA

IS - 7-8

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Antioxidant and antimicrobial activities of Onosma argentatum and Rubia peregrina

Abstract

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