Antioxidant and cytotoxic activities of Retama raetam subsp Gussonei

TY - JOUR

T1 - Antioxidant and cytotoxic activities of Retama raetam subsp Gussonei

AU - Conforti, F

AU - Statti, G

AU - Tundis, R

AU - Loizzo, M R

AU - Bonesi, M

AU - Menichini, F

AU - Houghton, P J

PY - 2004/7

Y1 - 2004/7

N2 - The aim of this study was to evaluate the in vitro antioxidant and cytotoxic activities of the methanol extracts of Retama raetam subsp. gussonei leaves and seeds. The antioxidant activity of the extracts was assessed by means of two different tests: (1) bleaching of the stable 2,2-diphenyl-1-pierylhydrazil (DPPH) radical; and (2) lipid peroxidation of liposomes which were prepared from bovine brain extract. In both tests used leaves extract showed a significant antioxidant effect. The extract of leaves also demonstrated a good cytotoxic activity against COR-L23 (large cell carcinoma) tell line. Copyright (C) 2004 John Wiley Sons, Ltd.

AB - The aim of this study was to evaluate the in vitro antioxidant and cytotoxic activities of the methanol extracts of Retama raetam subsp. gussonei leaves and seeds. The antioxidant activity of the extracts was assessed by means of two different tests: (1) bleaching of the stable 2,2-diphenyl-1-pierylhydrazil (DPPH) radical; and (2) lipid peroxidation of liposomes which were prepared from bovine brain extract. In both tests used leaves extract showed a significant antioxidant effect. The extract of leaves also demonstrated a good cytotoxic activity against COR-L23 (large cell carcinoma) tell line. Copyright (C) 2004 John Wiley Sons, Ltd.

UR - http://www.scopus.com/inward/record.url?scp=4043101804&partnerID=8YFLogxK

U2 - 10.1002/ptr.1496

DO - 10.1002/ptr.1496

M3 - Article

VL - 18

SP - 585

EP - 587

JO - PHYTOTHERAPY RESEARCH

JF - PHYTOTHERAPY RESEARCH

IS - 7

ER -