Abstract
This work presents the application of a quantitative magnetic resonance imaging (MRI) technique in stereotactic deep-brain neurosurgery planning procedures. The high spatial resolution T-1 and T-2 maps acquired using this imaging method have been normalized to the standard CJH-27 brain coordinate system and integrated into a neurosurgical visualization and navigation system to improve the accuracy of surgical target localization. The T-1 and T-2 maps, along with the standardized anatomical and functional information within this system, can be navigated, non-rigidly registered, and arbitrarily processed. Once applied to individual patients, these maps facilitate the delineation of surgical targets. Our preliminary studies compared the centroids of segmented deep-brain nuclei based on the T-1 and T-2 maps with those according to Schaltenbrand and Wahren atlas, and with the actual surgical targets of 15 patients who had undergone thalamotomy, pallidotomy, and subthalamic nucleus deep-brain stimulation. The average displacement was 3.21mm +/- 0.80mm, indicating the potential capability of this system to accurately initiate target identifications.
Original language | English |
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Title of host publication | 2005 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vols 1-7 |
Place of Publication | NEW YORK |
Publisher | IEEE |
Pages | 5416-5419 |
Number of pages | 4 |
Volume | 7 VOLS |
ISBN (Print) | 0-7803-8740-6 |
Publication status | Published - 2005 |
Event | 27th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society - Shanghai Duration: 31 Aug 2005 → 3 Sept 2005 |
Conference
Conference | 27th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society |
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City | Shanghai |
Period | 31/08/2005 → 3/09/2005 |