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Applications and Future Directions for Optical Coherence Tomography in Dermatology

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Applications and Future Directions for Optical Coherence Tomography in Dermatology. / Wan, B; Ganier, C; Du-Harpur, X; Harun, N; Watt, F M; Patalay, R; Lynch, M D.

In: The British journal of dermatology, 24.09.2020.

Research output: Contribution to journalReview article

Harvard

Wan, B, Ganier, C, Du-Harpur, X, Harun, N, Watt, FM, Patalay, R & Lynch, MD 2020, 'Applications and Future Directions for Optical Coherence Tomography in Dermatology', The British journal of dermatology. https://doi.org/10.1111/bjd.19553

APA

Wan, B., Ganier, C., Du-Harpur, X., Harun, N., Watt, F. M., Patalay, R., & Lynch, M. D. (2020). Applications and Future Directions for Optical Coherence Tomography in Dermatology. The British journal of dermatology. https://doi.org/10.1111/bjd.19553

Vancouver

Wan B, Ganier C, Du-Harpur X, Harun N, Watt FM, Patalay R et al. Applications and Future Directions for Optical Coherence Tomography in Dermatology. The British journal of dermatology. 2020 Sep 24. https://doi.org/10.1111/bjd.19553

Author

Wan, B ; Ganier, C ; Du-Harpur, X ; Harun, N ; Watt, F M ; Patalay, R ; Lynch, M D. / Applications and Future Directions for Optical Coherence Tomography in Dermatology. In: The British journal of dermatology. 2020.

Bibtex Download

@article{0a678917b71946e7aa60e2afe38f0943,
title = "Applications and Future Directions for Optical Coherence Tomography in Dermatology",
abstract = "Optical coherence tomography (OCT) is a non-invasive optical imaging method that can generate high-resolution en-face and cross-sectional images of the skin in vivo to a maximum depth of 2mm. Whilst OCT holds considerable potential for non-invasive diagnosis and disease monitoring, it is poorly understood by many dermatologists. Here, we aim to equip the practicing dermatologist with an understanding of the principles of skin OCT and the potential clinical indications. We begin with an introduction to the technology and discuss the different modalities of OCT including angiographic (dynamic) OCT, which can image cutaneous blood vessels at high resolution. Next we review clinical applications. OCT has been most extensively investigated in the diagnosis of keratinocyte carcinomas, particularly basal cell carcinoma (BCC). To date, OCT has not proven sufficiently accurate for the robust diagnosis of malignant melanoma, however the evaluation of abnormal vasculature with angiographic OCT is an area of active investigation. OCT and in particular angiographic OCT also show promise in monitoring the response of inflammatory dermatoses, such as psoriasis and connective tissues disease to therapy. We additionally discuss a potential role for artificial intelligence in improving the accuracy of interpretation of OCT imaging data.",
author = "B Wan and C Ganier and X Du-Harpur and N Harun and Watt, {F M} and R Patalay and Lynch, {M D}",
note = "This article is protected by copyright. All rights reserved.",
year = "2020",
month = sep,
day = "24",
doi = "10.1111/bjd.19553",
language = "English",
journal = "British Journal of Dermatology",
issn = "0007-0963",
publisher = "John Wiley & Sons, Ltd (10.1111)",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Applications and Future Directions for Optical Coherence Tomography in Dermatology

AU - Wan, B

AU - Ganier, C

AU - Du-Harpur, X

AU - Harun, N

AU - Watt, F M

AU - Patalay, R

AU - Lynch, M D

N1 - This article is protected by copyright. All rights reserved.

PY - 2020/9/24

Y1 - 2020/9/24

N2 - Optical coherence tomography (OCT) is a non-invasive optical imaging method that can generate high-resolution en-face and cross-sectional images of the skin in vivo to a maximum depth of 2mm. Whilst OCT holds considerable potential for non-invasive diagnosis and disease monitoring, it is poorly understood by many dermatologists. Here, we aim to equip the practicing dermatologist with an understanding of the principles of skin OCT and the potential clinical indications. We begin with an introduction to the technology and discuss the different modalities of OCT including angiographic (dynamic) OCT, which can image cutaneous blood vessels at high resolution. Next we review clinical applications. OCT has been most extensively investigated in the diagnosis of keratinocyte carcinomas, particularly basal cell carcinoma (BCC). To date, OCT has not proven sufficiently accurate for the robust diagnosis of malignant melanoma, however the evaluation of abnormal vasculature with angiographic OCT is an area of active investigation. OCT and in particular angiographic OCT also show promise in monitoring the response of inflammatory dermatoses, such as psoriasis and connective tissues disease to therapy. We additionally discuss a potential role for artificial intelligence in improving the accuracy of interpretation of OCT imaging data.

AB - Optical coherence tomography (OCT) is a non-invasive optical imaging method that can generate high-resolution en-face and cross-sectional images of the skin in vivo to a maximum depth of 2mm. Whilst OCT holds considerable potential for non-invasive diagnosis and disease monitoring, it is poorly understood by many dermatologists. Here, we aim to equip the practicing dermatologist with an understanding of the principles of skin OCT and the potential clinical indications. We begin with an introduction to the technology and discuss the different modalities of OCT including angiographic (dynamic) OCT, which can image cutaneous blood vessels at high resolution. Next we review clinical applications. OCT has been most extensively investigated in the diagnosis of keratinocyte carcinomas, particularly basal cell carcinoma (BCC). To date, OCT has not proven sufficiently accurate for the robust diagnosis of malignant melanoma, however the evaluation of abnormal vasculature with angiographic OCT is an area of active investigation. OCT and in particular angiographic OCT also show promise in monitoring the response of inflammatory dermatoses, such as psoriasis and connective tissues disease to therapy. We additionally discuss a potential role for artificial intelligence in improving the accuracy of interpretation of OCT imaging data.

U2 - 10.1111/bjd.19553

DO - 10.1111/bjd.19553

M3 - Review article

C2 - 32974943

JO - British Journal of Dermatology

JF - British Journal of Dermatology

SN - 0007-0963

ER -

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