Applied respiratory physiology

A D Milner, A Greenough

    Research output: Contribution to journalLiterature reviewpeer-review

    Abstract

    Respiratory failure, hypoxia with or without hypercarbia, is common in infants and children. Knowledge of the underlying abnormal physiology facilitates diagnosis and therapy. Isolated hypoxia can result from ventilation perfusion mismatch, intra- and extrapulmonary shunting and impaired diffusion. Intra- and extrapulmonary shunting can be distinguished from the other conditions by a poor response to supplementary oxygen. Hypercarbia indicates an inadequate minute ventilation which can result from upper or lower airway obstruction, reduced respiratory system compliance or conditions adversely affecting the respiratory pump. (C) 2002 Harcourt Publishers Ltd
    Original languageEnglish
    Pages (from-to)51 - 56
    Number of pages6
    JournalCurrent Paediatrics
    Volume12
    Issue number1
    Publication statusPublished - 2002

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