Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?

ERANID Consortium; IMAGEN Consortium

doi:10.1016/j.schres.2021.01.002

Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?

ERANID Consortium, IMAGEN Consortium

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Objective: To assess changes in cannabis use in young adults as a function of psychotic-like experiences. Method: Participants were initially recruited at age 14 in high schools for the longitudinal IMAGEN study. All measures presented here were assessed at follow-ups at age 19 and at age 22, respectively. Perceived stress was only assessed once at age 22. Ever users of cannabis (N = 552) gave qualitative and quantitative information on cannabis use and psychotic-like experiences using the Community Assessment of Psychic Experiences (CAPE). Of those, nearly all n = 549 reported to have experienced at least one psychotic experience of any form at age 19. Results: Mean cannabis use increased from age 19 to 22 and age of first use of cannabis was positively associated with a change in cannabis use between the two time points. Change in cannabis use was not significantly associated with psychotic-like experiences at age 19 or 22. In exploratory analysis, we observed a positive association between perceived stress and the experience of psychotic experiences at age 22. Conclusion: Age of first use of cannabis influenced trajectories of young cannabis users with later onset leading to higher increase, whereas the frequency of psychotic-like experiences was not associated with a change in cannabis use. The observed association between perceived stress and psychotic-like experiences at age 22 emphasizes the importance of stress experiences in developing psychosis independent of cannabis use.

Original language	English
Pages (from-to)	271-279
Number of pages	9
Journal	Schizophrenia Research
Volume	228
DOIs	https://doi.org/10.1016/j.schres.2021.01.002
Publication status	Published - Feb 2021

Keywords

Age of first use
Cannabis discontinuation hypothesis
Cannabis use
Perceived stress
Psychotic-like experiences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.schres.2021.01.002

Cite this

@article{6aa6f78d4b7d4c2294d92738c8810287,

title = "Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?",

abstract = "Objective: To assess changes in cannabis use in young adults as a function of psychotic-like experiences. Method: Participants were initially recruited at age 14 in high schools for the longitudinal IMAGEN study. All measures presented here were assessed at follow-ups at age 19 and at age 22, respectively. Perceived stress was only assessed once at age 22. Ever users of cannabis (N = 552) gave qualitative and quantitative information on cannabis use and psychotic-like experiences using the Community Assessment of Psychic Experiences (CAPE). Of those, nearly all n = 549 reported to have experienced at least one psychotic experience of any form at age 19. Results: Mean cannabis use increased from age 19 to 22 and age of first use of cannabis was positively associated with a change in cannabis use between the two time points. Change in cannabis use was not significantly associated with psychotic-like experiences at age 19 or 22. In exploratory analysis, we observed a positive association between perceived stress and the experience of psychotic experiences at age 22. Conclusion: Age of first use of cannabis influenced trajectories of young cannabis users with later onset leading to higher increase, whereas the frequency of psychotic-like experiences was not associated with a change in cannabis use. The observed association between perceived stress and psychotic-like experiences at age 22 emphasizes the importance of stress experiences in developing psychosis independent of cannabis use.",

keywords = "Age of first use, Cannabis discontinuation hypothesis, Cannabis use, Perceived stress, Psychotic-like experiences",

author = "{ERANID Consortium} and {IMAGEN Consortium} and Daedelow, {Laura S.} and Tobias Banaschewski and Moritz Berning and Bokde, {Arun L.W.} and R{\"u}diger Br{\"u}hl and {Burke Quinlan}, Erin and Curran, {H. Valerie} and Sylvane Desrivi{\`e}res and Herta Flor and Antoine Grigis and Hugh Garavan and Anita Hardon and Jakob Kaminski and Martinot, {Jean Luc} and {Paill{\`e}re Martinot}, {Marie Laure} and Eric Artiges and Hayley Murray and Frauke Nees and Oei, {Nicole Y.L.} and {Papadopoulos Orfanos}, Dimitri and Tom{\'a}{\v s} Paus and Luise Poustka and Sarah Hohmann and Sabina Millenet and Annika Rosenthal and Fr{\"o}hner, {Juliane H.} and Smolka, {Michael N.} and Henrik Walter and Robert Whelan and Wiers, {Reinout W.} and Gunter Schumann and Andreas Heinz",

year = "2021",

month = feb,

doi = "10.1016/j.schres.2021.01.002",

language = "English",

volume = "228",

pages = "271--279",

journal = "Schizophrenia Research",