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Are snoRNAs and snoRNA host genes new players in cancer?

    • Keele University

    Research output: Contribution to journalArticlepeer-review

    329 Citations (Scopus)

    Abstract

    Small nucleolar RNAs (snoRNAs) have long been considered important but unglamorous elements in the production of the protein synthesis machinery of the cell. Recently, however, several independent lines of evidence have indicated that these non-coding RNAs might have crucial roles in controlling cell behaviour, and snoRNA dysfunction could consequently contribute to oncogenesis in previously unsuspected ways.
    Original languageEnglish
    Article numberN/A
    Pages (from-to)84 - 88
    Number of pages5
    JournalNATURE REVIEWS CANCER
    Volume12
    Issue number2
    DOIs
    Publication statusPublished - Feb 2012

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Animals
    • Humans
    • Neoplasms
    • RNA Processing, Post-Transcriptional
    • RNA, Small Nucleolar

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