ASPI: a public-private partnership to develop treatments for autism

Seth Ness; Gahan Pandina; Shyla Jagannatha; Kyle Wathen; Abigail Bangerter; Nikolay V Manyakov; Robert L Hendren; Bennett L. Leventhal; Declan Murphy; Geraldine Dawson; Wayne C. Drevets; Husseini Manji

doi:10.1038/d41573-020-00012-4

ASPI: a public-private partnership to develop treatments for autism

Seth Ness, Gahan Pandina, Shyla Jagannatha, Kyle Wathen, Abigail Bangerter, Nikolay V Manyakov, Robert L Hendren, Bennett L. Leventhal, Declan Murphy, Geraldine Dawson, Wayne C. Drevets, Husseini Manji

Forensic & Neurodevelopmental Sciences

Research output: Contribution to journal › Comment/debate › peer-review

5 Citations (Scopus)

Abstract

Numerous potential therapeutic targets are being investigated in autism spectrum disorder (ASD). Here, we discuss a platform trial approach for designing proof-of-concept (POC) clinical studies of ASD — via the Autism Spectrum POC Initiative (ASPI) — that can be conducted through a public–private partnership with the aim of finding effective treatments in the most expeditious manner.

Original language	English
Pages (from-to)	219-220
Number of pages	2
Journal	Nature Reviews Drug Discovery
Volume	19
Issue number	4
DOIs	https://doi.org/10.1038/d41573-020-00012-4
Publication status	Published - 1 Apr 2020

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author = "Seth Ness and Gahan Pandina and Shyla Jagannatha and Kyle Wathen and Abigail Bangerter and Manyakov, {Nikolay V} and Hendren, {Robert L} and Leventhal, {Bennett L.} and Declan Murphy and Geraldine Dawson and Drevets, {Wayne C.} and Husseini Manji",

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AU - Ness, Seth

AU - Pandina, Gahan

AU - Jagannatha, Shyla

AU - Wathen, Kyle

AU - Bangerter, Abigail

AU - Manyakov, Nikolay V

AU - Hendren, Robert L

AU - Leventhal, Bennett L.

AU - Murphy, Declan

AU - Dawson, Geraldine

AU - Drevets, Wayne C.

AU - Manji, Husseini

PY - 2020/4/1

Y1 - 2020/4/1

N2 - Numerous potential therapeutic targets are being investigated in autism spectrum disorder (ASD). Here, we discuss a platform trial approach for designing proof-of-concept (POC) clinical studies of ASD — via the Autism Spectrum POC Initiative (ASPI) — that can be conducted through a public–private partnership with the aim of finding effective treatments in the most expeditious manner.

AB - Numerous potential therapeutic targets are being investigated in autism spectrum disorder (ASD). Here, we discuss a platform trial approach for designing proof-of-concept (POC) clinical studies of ASD — via the Autism Spectrum POC Initiative (ASPI) — that can be conducted through a public–private partnership with the aim of finding effective treatments in the most expeditious manner.

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U2 - 10.1038/d41573-020-00012-4

DO - 10.1038/d41573-020-00012-4

M3 - Comment/debate

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SP - 219

EP - 220

JO - Nature Reviews Drug Discovery

JF - Nature Reviews Drug Discovery

IS - 4

ER -

ASPI: a public-private partnership to develop treatments for autism

Abstract

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