Assessment of an Intermediate Reprojection Technique Transitioning from Planar to SPECT Radionuclide Ventriculography

James O'Doherty, Bruno Rojas-Fisher, Jonathan Price, Kshama Wechalekar

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Background
The technique of SPECT-RNV (radionuclide ventriculography) offers a greater amount of clinically usable data than its planar counterpart (P-RNV). In transitioning from planar to SPECT only acquisition methodologies, reprojection of the SPECT data can provide a planar dataset which can be used as an interim technique. The aim of this study was to test if reprojected planar images could be used as a surrogate for true planar images in SPECT only setting.
Methods
We performed SPECT-RNV and P-RNV on 47 patients on traditional sodium iodide (NaI) cameras, determining left ventricular ejection fractions (LVEF) for planar (EFP) and SPECT (EFS) techniques. We reprojected the SPECT-RNV data along the best septal separation angle determined from planar scanning. This creates a further planar dataset denoted “reprojected P-RNV” (rP-RNV) giving a reprojected ejection fraction (EFR) which can be used as a validation variable in transitioning to SPECT only acquisition.
Results
Performing t-tests showed no statistical difference between EFP and EFR, (p>0.017) but bias was observed in EFS results compared to EFP and EFS compared to EFR results. An un-blinded, comparison of parametric data between the three datasets for a subset of 10 patients showed good clinical concordance. False negative and false positive rates were low for rP-RNV compared to P-RNV.
Conclusions
The reprojected planar LVEF correlates well to P-RNV EF values. The rP-RNV dataset can aid clinicians in transitioning from planar RNV to SPECT only acquisition.
Original languageEnglish
Pages (from-to)944-953
Number of pages10
JournalJournal of Nuclear Cardiology
Volume21
Issue number5
Early online date1 Aug 2014
DOIs
Publication statusPublished - 1 Oct 2014

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